NP_001009185.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
long-chain-fatty-acid--CoA ligase 6 isoform b
NCBI Official Synonym Full Names
acyl-CoA synthetase long chain family member 6
NCBI Official Synonym Symbols
ACS2; FACL6; LACS2; LACS5; LACS 6 [Similar Products]
NCBI Protein Information
long-chain-fatty-acid--CoA ligase 6
UniProt Protein Name
Long-chain-fatty-acid--CoA ligase 6
UniProt Synonym Protein Names
Long-chain acyl-CoA synthetase 6; LACS 6
UniProt Synonym Gene Names
NCBI Summary for ACSL6
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
UniProt Comments for ACSL6
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Research Articles on ACSL6
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Products associated with anti-ACSL6 antibody
Pathways associated with anti-ACSL6 antibody
Diseases associated with anti-ACSL6 antibody
Organs/Tissues associated with anti-ACSL6 antibody
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