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anti-ACTR3 antibody :: Rabbit ACTR3 Antibody

Scan QR to view Datasheet Catalog #    MBS001425 anti-ACTR3 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACTR3, Antibody

 Also Known As   

Rabbit ACTR3 Antibody

 Product Gene Name   

anti-ACTR3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (114647537..114716167). Location: 2q14.1
 OMIM    604222
 3D Structure    ModBase 3D Structure for P61158
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-ACTR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ACTR3 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ACTR3. It may not necessarily be applicable to this product.
 NCBI GI #    5031573
 NCBI GeneID    10096
 NCBI Accession #    NP_005712.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005721.4 [Other Products]
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 UniProt Primary Accession #    P61158 [Other Products]
 UniProt Secondary Accession #    P32391; Q53QM2 [Other Products]
 UniProt Related Accession #    P61158 [Other Products]
 Molecular Weight    47,371 Da
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 NCBI Official Full Name    actin-related protein 3 isoform 1
 NCBI Official Synonym Full Names    ARP3 actin-related protein 3 homolog (yeast)
 NCBI Official Symbol    ACTR3 [Similar Products]
 NCBI Official Synonym Symbols   
ARP3
[Similar Products]
 NCBI Protein Information    actin-related protein 3; actin-like protein 3
 UniProt Protein Name    Actin-related protein 3
 UniProt Synonym Protein Names   
Actin-like protein 3
 UniProt Gene Name    ACTR3 [Similar Products]
 UniProt Synonym Gene Names    ARP3 [Similar Products]
 UniProt Entry Name    ARP3_HUMAN
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 NCBI Summary for ACTR3    The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
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 UniProt Comments for ACTR3    Arp3: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Belongs to the actin family. ARP3 subfamily.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q14.1

Cellular Component: Golgi membrane; Arp2/3 protein complex; focal adhesion; hemidesmosome; membrane; lamellipodium; excitatory synapse; actin filament; podosome; intercellular junction; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; ATP binding

Biological Process: positive regulation of filopodium formation; meiotic chromosome movement towards spindle pole; axon guidance; regulation of myosin II filament assembly or disassembly; establishment and/or maintenance of cell polarity; positive regulation of dendrite morphogenesis; cytokinesis after meiosis; response to carbohydrate stimulus; spindle localization; response to antibiotic; asymmetric cell division; ephrin receptor signaling pathway; innate immune response; cell motility
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 Research Articles on ACTR3    1. Study suggested that positive CFL1 and Arp3 expression are closely related to tumor progression, metastasis, and poor prognosis of gallbladder cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ACTR3 antibodyPathways associated with anti-ACTR3 antibody
 Reference Product  PubMed Publications
 ACTR2 antibody  >149 publications with ACTR3 and ACTR2
 CDC42 antibody  >31 publications with ACTR3 and CDC42
 CTTN antibody  >17 publications with ACTR3 and CTTN
 WASF2 antibody  >2 publications with ACTR3 and WASF2
 ARPC5 antibody  >2 publications with ACTR3 and ARPC5
 WASF3 antibody  >1 publications with ACTR3 and WASF3
 ARPC3 antibody  >1 publications with ACTR3 and ARPC3
 ARPC2 antibody  >1 publications with ACTR3 and ARPC2
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 RAC1 Signaling Pathway antibodies  RAC1 Signaling Pathway Diagram
 Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies  Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram
Diseases associated with anti-ACTR3 antibodyOrgans/Tissues associated with anti-ACTR3 antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >4 publications with ACTR3 and Neoplasm Metastasis
 Urogenital Abnormalities Antibodies  >1 publications with ACTR3 and Urogenital Abnormalities
 Fibrosis Antibodies  >1 publications with ACTR3 and Fibrosis
 Poisoning Antibodies  >1 publications with ACTR3 and Poisoning
 Proteinuria Antibodies  >1 publications with ACTR3 and Proteinuria
 Necrosis Antibodies  >1 publications with ACTR3 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >25 publications with ACTR3 and Blood
 Muscle Antibodies  >15 publications with ACTR3 and Muscle
 Brain Antibodies  >12 publications with ACTR3 and Brain
 Stomach Antibodies  >4 publications with ACTR3 and Stomach
 Bone Antibodies  >3 publications with ACTR3 and Bone
 Lung Antibodies  >3 publications with ACTR3 and Lung
 Kidney Antibodies  >2 publications with ACTR3 and Kidney
 Thymus Antibodies  >2 publications with ACTR3 and Thymus
 Bone Marrow Antibodies  >2 publications with ACTR3 and Bone Marrow
 Pancreas Antibodies  >1 publications with ACTR3 and Pancreas
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