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anti-ADCY5 antibody :: ADCY5 Antibody

Scan QR to view Datasheet Catalog #    MBS852349
Western Blot (WB)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADCY5, Antibody

 Also Known As   

ADCY5 Antibody

 Product Synonym Names    ATP pyrophosphate-lyase 5; Adenylate cyclase type 5; Adenylate cyclase type V; Adenylyl cyclase 5
 Product Gene Name   

anti-ADCY5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600293
 3D Structure    ModBase 3D Structure for O95622
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    ADCY5 antibody detects endogenous levels of total ADCY5 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human ADCY5.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-ADCY5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ADCY5 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-ADCY5 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-ADCY5 antibody    WB: 1:500-1:1000
ELISA: 1:10000
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 Western Blot (WB) of anti-ADCY5 antibody    Western blot analysis of extracts from COLO205 cells, using ADCY5 antibody.
anti-ADCY5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ADCY5. It may not necessarily be applicable to this product.
 NCBI GI #    314122162
 NCBI GeneID    111
 NCBI Accession #    NP_001186571.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199642.1 [Other Products]
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 UniProt Primary Accession #    O95622 [Other Products]
 UniProt Secondary Accession #    Q7RTV7; Q8NFM3; B7Z8A6 [Other Products]
 UniProt Related Accession #    O95622 [Other Products]
 Molecular Weight    102,606 Da
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 NCBI Official Full Name    adenylate cyclase type 5 isoform 2
 NCBI Official Synonym Full Names    adenylate cyclase 5
 NCBI Official Symbol    ADCY5 [Similar Products]
 NCBI Official Synonym Symbols   
AC5; FDFM
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 5
 UniProt Protein Name    Adenylate cyclase type 5
 UniProt Synonym Protein Names   
ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; AC5
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY5 [Similar Products]
 UniProt Synonym Gene Names    AC5 [Similar Products]
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 NCBI Summary for ADCY5    This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
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 UniProt Comments for ADCY5    Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).
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Product References and Citations for anti-ADCY5 antibody

   Muzny D.M., Nature 440:1194-1198(2006). Ludwig M.G., J. Recept. Signal Transduct. Res. 22:79-110(2002). Raimundo S., Clin. Chim. Acta 285:155-161(1999).
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 Research Articles on ADCY5    1. Mutations in ADCY5 are responsible for a hyperkinetic movement disorder that can be preceded by episodic attacks before the movement disorder becomes persistent and is frequently misdiagnosed as dyskinetic cerebral palsy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADCY5 antibodyPathways associated with anti-ADCY5 antibody
 Reference Product  PubMed Publications
 ADRA2A antibody  >6 publications with ADCY5 and ADRA2A
 MTNR1B antibody  >5 publications with ADCY5 and MTNR1B
 GIPR antibody  >4 publications with ADCY5 and GIPR
 ADCY2 antibody  >2 publications with ADCY5 and ADCY2
 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
Diseases associated with anti-ADCY5 antibodyOrgans/Tissues associated with anti-ADCY5 antibody
 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >13 publications with ADCY5 and Diabetes Mellitus, Type 2
 Birth Weight Antibodies  >8 publications with ADCY5 and Birth Weight
 Nervous System Diseases Antibodies  >2 publications with ADCY5 and Nervous System Diseases
 Depressive Disorder Antibodies  >1 publications with ADCY5 and Depressive Disorder
 Substance Withdrawal Syndrome Antibodies  >1 publications with ADCY5 and Substance Withdrawal Syndrome
 Movement Disorders Antibodies  >1 publications with ADCY5 and Movement Disorders
 Hypertension Antibodies  >1 publications with ADCY5 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with ADCY5 and Blood
 Heart Antibodies  >3 publications with ADCY5 and Heart
 Nerve Antibodies  >2 publications with ADCY5 and Nerve
 Brain Antibodies  >2 publications with ADCY5 and Brain
 Lung Antibodies  >1 publications with ADCY5 and Lung
 Prostate Antibodies  >1 publications with ADCY5 and Prostate
 Pancreas Antibodies  >1 publications with ADCY5 and Pancreas
 Placenta Antibodies  >1 publications with ADCY5 and Placenta
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