AAI00796.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,136 Da
NCBI Official Full Name
AMICA1 protein
NCBI Official Synonym Full Names
adhesion molecule, interacts with CXADR antigen 1
NCBI Official Synonym Symbols
JAML; AMICA; Gm638; CREA7-1; CREA7-4 [Similar Products]
NCBI Protein Information
junctional adhesion molecule-like
UniProt Protein Name
Junctional adhesion molecule-like
UniProt Synonym Protein Names
Adhesion molecule interacting with CXADR antigen 1; Dendritic cell-specific protein CREA7-1
UniProt Synonym Gene Names
UniProt Entry Name
JAML1_HUMAN
UniProt Comments for AMICA1
AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: tight junction; plasma membrane; integral to membrane
Molecular Function: integrin binding; protein homodimerization activity; cell adhesion molecule binding
Biological Process: heterophilic cell adhesion; neutrophil chemotaxis; regulation of immune response; positive regulation of epithelial cell proliferation involved in wound healing; blood coagulation; leukocyte migration; gamma-delta T cell activation
Research Articles on AMICA1
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Pathways associated with anti-AMICA1 antibody
Diseases associated with anti-AMICA1 antibody
Organs/Tissues associated with anti-AMICA1 antibody
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