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anti-ARF6 antibody :: Rabbit ARF6 Antibody

Scan QR to view Datasheet Catalog #    MBS004339 anti-ARF6 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARF6, Antibody

 Also Known As   

Rabbit ARF6 Antibody

 Product Gene Name   

anti-ARF6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_000014.8 (50359736..50363772). Location: 14q21.3
 OMIM    600464
 3D Structure    ModBase 3D Structure for P62330
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-ARF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ARF6 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ARF6. It may not necessarily be applicable to this product.
 NCBI GI #    4502211
 NCBI GeneID    382
 NCBI Accession #    NP_001654.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001663.3 [Other Products]
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 UniProt Primary Accession #    P62330 [Other Products]
 UniProt Secondary Accession #    P26438; Q6FGZ2 [Other Products]
 UniProt Related Accession #    P62330 [Other Products]
 Molecular Weight    20,082 Da
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 NCBI Official Full Name    ADP-ribosylation factor 6
 NCBI Official Synonym Full Names    ADP-ribosylation factor 6
 NCBI Official Symbol    ARF6 [Similar Products]
 NCBI Protein Information    ADP-ribosylation factor 6
 UniProt Protein Name    ADP-ribosylation factor 6
 Protein Family    Auxin response factor
 UniProt Gene Name    ARF6 [Similar Products]
 UniProt Entry Name    ARF6_HUMAN
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 NCBI Summary for ARF6    This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARF6    ARF6: GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development. Contributes to the regulation of dendritic branching and filopodia extension. Interacts with ARHGAP21, ASAP2, HERC1, PIP5K1C and UACA. Interacts with NCS1/FREQ at the plasma membrane. Interacts with RAB11FIP3 and RAB11FIP4. Interacts with USP6 (via Rab-GAP TBC domain). Interacts with ECM29. Interacts with TBC1D24. Belongs to the small GTPase superfamily. Arf family.

Protein type: G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, ARF

Chromosomal Location of Human Ortholog: 14q21.3

Cellular Component: Golgi apparatus; ruffle; filopodium membrane; focal adhesion; membrane; endocytic vesicle; recycling endosome membrane; early endosome; plasma membrane; cell cortex; midbody; endosome; cleavage furrow

Molecular Function: GTPase activity; protein binding; GTP binding; thioesterase binding

Biological Process: myeloid cell apoptosis; metabolic process; regulation of filopodium formation; liver development; cell cycle; vesicle-mediated transport; regulation of Rac protein signal transduction; protein transport; positive regulation of actin filament polymerization; cell division; small GTPase mediated signal transduction; ruffle organization and biogenesis; negative regulation of receptor-mediated endocytosis; cortical actin cytoskeleton organization and biogenesis; cell adhesion; cell motility
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 Research Articles on ARF6    1. Our studies implicate the small regulatory GTPase Arf6 in the endocytic trafficking of Pasteurella multocida toxin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARF6 antibodyPathways associated with anti-ARF6 antibody
 Reference Product  PubMed Publications
 PLD1 antibody  >21 publications with ARF6 and PLD1
 ASAP3 antibody  >4 publications with ARF6 and ASAP3
 ASAP2 antibody  >4 publications with ARF6 and ASAP2
 CYTH2 antibody  >3 publications with ARF6 and CYTH2
 ARFIP2 antibody  >3 publications with ARF6 and ARFIP2
 RAB11FIP3 antibody  >1 publications with ARF6 and RAB11FIP3
 AP3B1 antibody  >1 publications with ARF6 and AP3B1
 Products by Pathway  Pathway Diagram
 Arf6 Downstream Pathway antibodies  Arf6 Downstream Pathway Diagram
 Arf6 Signaling Events Pathway antibodies  Arf6 Signaling Events Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 E-cadherin Signaling In The Nascent Adherens Junction Pathway antibodies  E-cadherin Signaling In The Nascent Adherens Junction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
Diseases associated with anti-ARF6 antibodyOrgans/Tissues associated with anti-ARF6 antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >13 publications with ARF6 and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >6 publications with ARF6 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with ARF6 and Neoplasms, Experimental
 Cell Transformation, Neoplastic Antibodies  >5 publications with ARF6 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >5 publications with ARF6 and Inflammation
 Disease Models, Animal Antibodies  >4 publications with ARF6 and Disease Models, Animal
 Drug Toxicity Antibodies  >3 publications with ARF6 and Drug Toxicity
 Carcinoma, Hepatocellular Antibodies  >3 publications with ARF6 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >3 publications with ARF6 and Liver Diseases
 Embryo Loss Antibodies  >3 publications with ARF6 and Embryo Loss
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >62 publications with ARF6 and Blood
 Brain Antibodies  >57 publications with ARF6 and Brain
 Lung Antibodies  >28 publications with ARF6 and Lung
 Heart Antibodies  >25 publications with ARF6 and Heart
 Muscle Antibodies  >23 publications with ARF6 and Muscle
 Liver Antibodies  >11 publications with ARF6 and Liver
 Connective Tissue Antibodies  >5 publications with ARF6 and Connective Tissue
 Eye Antibodies  >5 publications with ARF6 and Eye
 Pancreas Antibodies  >5 publications with ARF6 and Pancreas
 Ear Antibodies  >4 publications with ARF6 and Ear
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