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anti-ARHGEF11 antibody :: ARHGEF11 Antibody

Scan QR to view Datasheet Catalog #    MBS854235
Western Blot (WB)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARHGEF11, Antibody

★Popular Item★
 Also Known As   

ARHGEF11 Antibody

 Product Synonym Names    ARHGB; glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RhoGEF; rho guanine exchange factor (GEF) 11; rhoA-specific guanine nucleotide exchange factor; rhoGEF glutamate transport modulator
 Product Gene Name   

anti-ARHGEF11 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605708
 3D Structure    ModBase 3D Structure for O15085
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    ARHGEF11 antibody detects endogenous levels of total ARHGEF11 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from N-terminal of human ARHGEF11.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-ARHGEF11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ARHGEF11 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-ARHGEF11 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-ARHGEF11 antibody    WB: 1:500~1:1000
ELISA: 1:5000
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 Western Blot (WB) of anti-ARHGEF11 antibody    Western blot analysis of extracts from A549 cells and COLO 205 cells, using ARHGEF11 antibody.
anti-ARHGEF11 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ARHGEF11. It may not necessarily be applicable to this product.
 NCBI GI #    7662086
 NCBI GeneID    9826
 NCBI Accession #    NP_055599.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014784.3 [Other Products]
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 UniProt Primary Accession #    O15085 [Other Products]
 UniProt Secondary Accession #    Q5VY40; Q6PFW2; D3DVD0 [Other Products]
 UniProt Related Accession #    O15085 [Other Products]
 Molecular Weight    172,244 Da
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 NCBI Official Full Name    rho guanine nucleotide exchange factor 11 isoform 1
 NCBI Official Synonym Full Names    Rho guanine nucleotide exchange factor 11
 NCBI Official Symbol    ARHGEF11 [Similar Products]
 NCBI Official Synonym Symbols   
GTRAP48; PDZ-RHOGEF
[Similar Products]
 NCBI Protein Information    rho guanine nucleotide exchange factor 11
 UniProt Protein Name    Rho guanine nucleotide exchange factor 11
 UniProt Synonym Protein Names   
PDZ-RhoGEF
 Protein Family    Rho guanine nucleotide exchange factor
 UniProt Gene Name    ARHGEF11 [Similar Products]
 UniProt Synonym Gene Names    KIAA0380 [Similar Products]
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 NCBI Summary for ARHGEF11    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARHGEF11    May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.
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Product References and Citations for anti-ARHGEF11 antibody

   Nagase T., DNA Res. 4:141-150(1997). Gregory S.G., Nature 441:315-321(2006). Ruemenapp U., FEBS Lett. 459:313-318(1999).
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 Research Articles on ARHGEF11    1. PAK4 (but not PAK1) mediates invadopodia maturation during melanoma invasion likely via inhibition of PDZ-RhoGEF.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARHGEF11 antibodyPathways associated with anti-ARHGEF11 antibody
 Reference Product  PubMed Publications
 RHOA antibody  >15 publications with ARHGEF11 and RHOA
 PLXNB1 antibody  >3 publications with ARHGEF11 and PLXNB1
 SLC1A6 antibody  >1 publications with ARHGEF11 and SLC1A6
 ABCA1 antibody  >1 publications with ARHGEF11 and ABCA1
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Regulation Of RhoA Activity Pathway antibodies  Regulation Of RhoA Activity Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Sema4D In Semaphorin Signaling Pathway antibodies  Sema4D In Semaphorin Signaling Pathway Diagram
 Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies  Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
Diseases associated with anti-ARHGEF11 antibodyOrgans/Tissues associated with anti-ARHGEF11 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with ARHGEF11 and Neoplasms
 Lung Neoplasms Antibodies  >1 publications with ARHGEF11 and Lung Neoplasms
 Genital Diseases, Male Antibodies  >1 publications with ARHGEF11 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >1 publications with ARHGEF11 and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with ARHGEF11 and Brain
 Kidney Antibodies  >4 publications with ARHGEF11 and Kidney
 Nerve Antibodies  >3 publications with ARHGEF11 and Nerve
 Blood Antibodies  >3 publications with ARHGEF11 and Blood
 Ganglia Antibodies  >1 publications with ARHGEF11 and Ganglia
 Uterus Antibodies  >1 publications with ARHGEF11 and Uterus
 Prostate Antibodies  >1 publications with ARHGEF11 and Prostate
 Embryonic Tissue Antibodies  >1 publications with ARHGEF11 and Embryonic Tissue
 Lung Antibodies  >1 publications with ARHGEF11 and Lung
 Ear Antibodies  >1 publications with ARHGEF11 and Ear
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