NP_001012301.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,030 Da
NCBI Official Full Name
arylsulfatase I
NCBI Official Synonym Full Names
arylsulfatase family, member I
NCBI Protein Information
arylsulfatase I; ASI
UniProt Protein Name
Arylsulfatase I
UniProt Synonym Gene Names
UniProt Entry Name
ARSI_HUMAN
NCBI Summary for ARSI
Sulfatases (EC 3.1.5.6), such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]
UniProt Comments for ARSI
ARSI: Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. Belongs to the sulfatase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; EC 3.1.6.-; Secreted, signal peptide; Hydrolase; Calcium-binding
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: endoplasmic reticulum lumen; extracellular region
Molecular Function: arylsulfatase activity; metal ion binding
Biological Process: cellular protein metabolic process; sphingolipid metabolic process; glycosphingolipid metabolic process; post-translational protein modification
Research Articles on ARSI
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Pathways associated with anti-ARSI antibody
Diseases associated with anti-ARSI antibody
Organs/Tissues associated with anti-ARSI antibody
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