NP_001034451.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
V-type proton ATPase subunit C 2 isoform a
NCBI Official Synonym Full Names
ATPase H+ transporting V1 subunit C2
NCBI Official Synonym Symbols
NCBI Protein Information
V-type proton ATPase subunit C 2
UniProt Protein Name
V-type proton ATPase subunit C 2
UniProt Synonym Protein Names
Vacuolar proton pump subunit C 2
UniProt Synonym Gene Names
NCBI Summary for ATP6V1C2
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for ATP6V1C2
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Research Articles on ATP6V1C2
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Pathways associated with anti-ATP6V1C2 antibody
Diseases associated with anti-ATP6V1C2 antibody
Organs/Tissues associated with anti-ATP6V1C2 antibody
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