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anti-AZI2 antibody :: Rabbit AZI2 Antibody

Scan QR to view Datasheet Catalog #    MBS001970
Western Blot
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AZI2, Antibody

 Also Known As   

Rabbit AZI2 Antibody

 Product Gene Name   

anti-AZI2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3; NC_000003.11 (28363845..28390618, complement). Location: 3p24.1
 OMIM    609916
 3D Structure    ModBase 3D Structure for Q9H6S1
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Specificity    AZI2 antibody detects endogenous levels of total AZI2 protein.
 Purity/Purification    The antibody was affinity-purifed from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Immunogen:    The antiserum was prduced against synthesized peptide dervied from N-terminal of human AZI2.
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 Preparation and Storage    Store at -20 deg. C/ 1 year
 Other Notes    Small volumes of anti-AZI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-AZI2 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-AZI2 antibody    WB: 1:500~1:3000; ELISA: 1:20000
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 Western Blot of anti-AZI2 antibody    anti-AZI2 antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for AZI2. It may not necessarily be applicable to this product.
 NCBI GI #    11968003
 NCBI GeneID    64343
 NCBI Accession #    NP_071906.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022461.4 [Other Products]
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 UniProt Primary Accession #    Q9H6S1 [Other Products]
 UniProt Secondary Accession #    Q86W99; Q9BQF1; A8K3M2 [Other Products]
 UniProt Related Accession #    Q9H6S1 [Other Products]
 Molecular Weight    44,935 Da
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 NCBI Official Full Name    5-azacytidine-induced protein 2 isoform a
 NCBI Official Synonym Full Names    5-azacytidine induced 2
 NCBI Official Symbol    AZI2 [Similar Products]
 NCBI Official Synonym Symbols   
AZ2; NAP1; TILP
[Similar Products]
 NCBI Protein Information    5-azacytidine-induced protein 2; NAK-associated protein 1; 5-azacytidine induced gene 2; NF-kappa-B-activating kinase-associated protein 1
 UniProt Protein Name    5-azacytidine-induced protein 2
 UniProt Synonym Protein Names   
NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP
 Protein Family    5-azacytidine-induced protein
 UniProt Gene Name    AZI2 [Similar Products]
 UniProt Synonym Gene Names    NAP1; Nak-associated protein 1 [Similar Products]
 UniProt Entry Name    AZI2_HUMAN
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 NCBI Summary for AZI2    AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for AZI2    AZI2: Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3p24.1

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: tumor necrosis factor production; I-kappaB kinase/NF-kappaB cascade; T cell activation; interleukin-6 production; interferon-gamma production; mitotic cell cycle; interferon-alpha production
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 Research Articles on AZI2    1. the spatiotemporal mobilization of TICAM-1 in response to dsRNA and the formation of the TICAM-1 speckles containing RIP1 and NAP1 are important for the activation of the TLR3-TICAM-1 pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AZI2 antibodyPathways associated with anti-AZI2 antibody
 Reference Product  PubMed Publications
 TBK1 antibody  >2 publications with AZI2 and TBK1
 IKBKE antibody  >1 publications with AZI2 and IKBKE
 Products by Pathway  Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram
 TNF-alpha/NF-kB Signaling Pathway antibodies  TNF-alpha/NF-kB Signaling Pathway Diagram
Organs/Tissues associated with anti-AZI2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with AZI2 and Bone
 Heart Antibodies  >1 publications with AZI2 and Heart
 Bone Marrow Antibodies  >1 publications with AZI2 and Bone Marrow
 Muscle Antibodies  >1 publications with AZI2 and Muscle
 Embryonic Tissue Antibodies  >1 publications with AZI2 and Embryonic Tissue
 Brain Antibodies  >1 publications with AZI2 and Brain
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