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PLIN2 antibody :: Adipophilin/Perilipin-2 Antibody

Scan QR to view Datasheet Catalog #    MBS439881
Unit / Price
0.02 mg (With BSA & Azide at 0.2mg/ml)  /  $190 +1 FREE 8GB USB
0.1 mg (With BSA & Azide at 0.2mg/ml)  /  $300 +1 FREE 8GB USB
0.1 mg (Without BSA & Azide at 1mg/ml)  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adipophilin/Perilipin-2 (PLIN2), Antibody

★Popular Item★
 Also Known As   

Adipophilin/Perilipin-2 (Marker of Obesity)

 Product Synonym Names    Adipophilin; ADFP; Adipose differentiation-related protein (ADRP); Perilipin-2 (PLIN2)
 Product Gene Name   

PLIN2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q99541
 Clonality    Monoclonal
 Isotype    IgG1, kappa
 Clone Number    ADFP/1365
 Host    Mouse
 Species Reactivity    Human. Others not known.
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 Specificity    Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
 Form/Format    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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 Immunogen    Recombinant human Adipophilin protein fragment (aa249-376)
 Cellular Localization    Cytoplasmic
 Hu-chromosome Location    9p22.1
 Positive Control    HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.
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 Preparation and Storage    Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
 Other Notes    Small volumes of PLIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for PLIN2 antibody   

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)

 Application Notes for PLIN2 antibody    FC/FACS: 0.5-1ug/million cells
IF: 0.5-1ug/ml
WB: 0.5-1ug/ml
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 Western Blot (WB) of PLIN2 antibody    Western Blot of recombinant Adipophilin and Jurkat Cell Lysate using Adipophilin Monoclonal Antibody (ADFP/1365).
PLIN2 antibody  Western Blot (WB) (WB) image
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 Flow Cytometry (FC/FACS) of PLIN2 antibody    Flow Cytometry of human Adipophilin on PBMC. Green: Isotype Control; Red: Adipophilin Monoclonal Antibody (ADFP/1365).
PLIN2 antibody  Flow Cytometry (FC/FACS) (FC/FACS) image
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NCBI/Uniprot data below describe general gene information for PLIN2. It may not necessarily be applicable to this product.
 NCBI GI #    34577059
 NCBI GeneID    123
 NCBI Accession #    NP_001113.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001122.3 [Other Products]
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 UniProt Primary Accession #    Q99541 [Other Products]
 UniProt Secondary Accession #    Q9BSC3 [Other Products]
 UniProt Related Accession #    Q99541 [Other Products]
 Molecular Weight    48kDa
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 NCBI Official Full Name    perilipin-2
 NCBI Official Synonym Full Names    perilipin 2
 NCBI Official Symbol    PLIN2 [Similar Products]
 NCBI Official Synonym Symbols   
ADFP; ADRP
[Similar Products]
 NCBI Protein Information    perilipin-2
 UniProt Protein Name    Perilipin-2
 UniProt Synonym Protein Names   
Adipophilin; Adipose differentiation-related protein; ADRP
 Protein Family    Perilipin
 UniProt Gene Name    PLIN2 [Similar Products]
 UniProt Synonym Gene Names    ADFP; ADRP [Similar Products]
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 NCBI Summary for PLIN2    The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
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 UniProt Comments for PLIN2    May be involved in development and maintenance of adipose tissue.
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Product References and Citations for PLIN2 antibody

   Kern, P.A., et al. 2004. Perilipin expression in human adipose tissue is elevated with obesity. J. Clin. Endocrinol. Metab. 89: 1352-1358.
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 Research Articles on PLIN2    1. ADRP knockdown significantly inhibited PDGFinduced increases in Vascular smooth muscle cell viability, caused G1 phase cell cycle arrest and decreased PCNA expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PLIN2 antibody Pathways associated with PLIN2 antibody
 Reference Product  PubMed Publications
 PPARA antibody  >2 publications with PLIN2 and PPARA
 CARM1 antibody  >1 publications with PLIN2 and CARM1
 RXRA antibody  >1 publications with PLIN2 and RXRA
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
Diseases associated with PLIN2 antibody Organs/Tissues associated with PLIN2 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >12 publications with PLIN2 and Fatty Liver
 Liver Diseases Antibodies  >7 publications with PLIN2 and Liver Diseases
 Inflammation Antibodies  >5 publications with PLIN2 and Inflammation
 Kidney Diseases Antibodies  >4 publications with PLIN2 and Kidney Diseases
 Adenocarcinoma Antibodies  >3 publications with PLIN2 and Adenocarcinoma
 Atrophy Antibodies  >2 publications with PLIN2 and Atrophy
 Breast Neoplasms Antibodies  >2 publications with PLIN2 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >2 publications with PLIN2 and Cardiovascular Diseases
 Fibrosis Antibodies  >1 publications with PLIN2 and Fibrosis
 Weight Loss Antibodies  >1 publications with PLIN2 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >21 publications with PLIN2 and Muscle
 Liver Antibodies  >14 publications with PLIN2 and Liver
 Blood Antibodies  >12 publications with PLIN2 and Blood
 Adipose Tissue Antibodies  >12 publications with PLIN2 and Adipose Tissue
 Mammary Gland Antibodies  >5 publications with PLIN2 and Mammary Gland
 Bone Antibodies  >5 publications with PLIN2 and Bone
 Connective Tissue Antibodies  >4 publications with PLIN2 and Connective Tissue
 Kidney Antibodies  >4 publications with PLIN2 and Kidney
 Heart Antibodies  >2 publications with PLIN2 and Heart
 Skin Antibodies  >2 publications with PLIN2 and Skin
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