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anti-ALB antibody :: Goat Albumin Antibody

Scan QR to view Datasheet Catalog #    MBS390003 anti-ALB antibody
Unit / Price
0.5 mL  /  $250 +1 FREE 8GB USB
1 mL  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Albumin, Antibody

 Also Known As   

Biotinylated Goat Anti-Human Albumin

 Product Synonym Names    Biotinylated Goat Anti-Human Albumin, Polyclonal Antibody
 Product Gene Name   

anti-ALB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 4; NC_000004.11 (74269972..74287129). Location: 4q13.3
 OMIM    103600
 3D Structure    ModBase 3D Structure for P02768
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 Host    Goat
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 Specificity    Specifically binds to Human Albumin. Dilution for immunoblot and ELISA range: 200 to 20,000
 Form/Format    0.5 ml in Freeze-dried powder
 Concentration    1 mg / ml (lot specific)
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 Source Note    Polyclonal goat anti-Human Albumin purified by Human Albumin -Sepharose affinity column and labeled with Biotin
 Preservative    75 mM PBS, 75 M NaCl, 0.02% NaN3, 0.5 mM EDTA, pH 7.2.
 Stabilizer    10 mg / ml Bovine Serum Albumin.
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 Preparation and Storage    Freeze-dried product should be stored refrigerated until opened. After opening, restore to 0.5 ml with distilled water. If it is not completely clear after standing for 1-2 Hours at room temperature, centrifuge the product. It is stable for several weeks at 4oC as an undiluted liquid. Do not use for more than one day after dilution. For extended storage after reconstitution, we suggest aliquot to avoid repeated freezing and thawing; or the addition of an equal volume of glycerol to make a final glycerol concentration of 50%, followed by storage at -20oC. The concentration of protein and buffer salts will decrease to one-half of the original after the addition of glycerol
 Other Notes    Small volumes of anti-ALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ALB antibody    Biotin Antibodies
 Applications Tested/Suitable for anti-ALB antibody   

ELISA (EIA), Immunoblot (IB)

 Application Notes for anti-ALB antibody    Freeze-dried powder. Dilution for Immunoblot & ELISA range: 1,000 to 20,000.
Use: The antibody can be used for detection of albumin in human plasma, immunoassays and immunoblots.
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NCBI/Uniprot data below describe general gene information for ALB. It may not necessarily be applicable to this product.
 NCBI GI #    412163
 NCBI GeneID    213
 NCBI Accession #    CAA00606.1 [Other Products]
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 UniProt Primary Accession #    P02768 [Other Products]
 UniProt Secondary Accession #    O95574; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0 [Other Products]
 UniProt Related Accession #    P02768 [Other Products]
 Molecular Weight    69,367 Da [Similar Products]
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 NCBI Official Full Name    albumin
 NCBI Official Synonym Full Names    albumin
 NCBI Official Symbol    ALB [Similar Products]
 NCBI Official Synonym Symbols   
PRO0883; PRO0903; PRO1341
[Similar Products]
 NCBI Protein Information    serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42
 UniProt Protein Name    Serum albumin
 Protein Family    Albumin
 UniProt Gene Name    ALB [Similar Products]
 UniProt Entry Name    ALBU_HUMAN
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 NCBI Summary for ALB    Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ALB    Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Ref.32

Subcellular location: Secreted.

Tissue specificity: Plasma.

Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracellular medium.Acetylated on Lys-223 by acetylsalicylic acid.

Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A.

Involvement in disease: Familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]: Form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.61 Ref.62 Ref.63 Ref.64

Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains.

Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulate fat digestion, lipid absorption, and blood flow.

Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
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 Research Articles on ALB    1. the (1)H-NMR relaxometric study of Mn(II) binding to HSA is reported. Mn(II) binding to HSA is modulated by Zn(II), pH, and myristate through competitive inhibition and allosteric mechanisms.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ALB antibodyDiseases associated with anti-ALB antibody
 Products by Pathway  Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >258 publications with ALB and Kidney Diseases
 Proteinuria Antibodies  >175 publications with ALB and Proteinuria
 Cardiovascular Diseases Antibodies  >172 publications with ALB and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >164 publications with ALB and Disease Models, Animal
 Liver Cirrhosis Antibodies  >137 publications with ALB and Liver Cirrhosis
 Respiratory Tract Diseases Antibodies  >123 publications with ALB and Respiratory Tract Diseases
 Brain Diseases Antibodies  >91 publications with ALB and Brain Diseases
 Kidney Failure, Chronic Antibodies  >69 publications with ALB and Kidney Failure, Chronic
 Hypertension Antibodies  >68 publications with ALB and Hypertension
 Nephritis Antibodies  >48 publications with ALB and Nephritis
Organs/Tissues associated with anti-ALB antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1276 publications with ALB and Blood
 Liver Antibodies  >714 publications with ALB and Liver
 Kidney Antibodies  >349 publications with ALB and Kidney
 Lung Antibodies  >123 publications with ALB and Lung
 Heart Antibodies  >112 publications with ALB and Heart
 Muscle Antibodies  >108 publications with ALB and Muscle
 Spleen Antibodies  >50 publications with ALB and Spleen
 Embryonic Tissue Antibodies  >42 publications with ALB and Embryonic Tissue
 Placenta Antibodies  >8 publications with ALB and Placenta
 Uterus Antibodies  >5 publications with ALB and Uterus
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