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anti-BAD antibody :: Rabbit anti-Mouse, rat BAD (Cleaved-Asp71) Antibody

Scan QR to view Datasheet Catalog #    MBS002571 anti-BAD antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BAD (Cleaved-Asp71), Antibody

 Also Known As   

Rabbit BAD (Cleaved-Asp71) Antibody

 Product Gene Name   

anti-BAD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000085.6 (6941855..6951893). Location: 19 A; 19
 3D Structure    ModBase 3D Structure for Q61337
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 Host    Rabbit
 Species Reactivity    Mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-BAD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BAD antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for BAD. It may not necessarily be applicable to this product.
 NCBI GI #    6671610
 NCBI GeneID    12015
 NCBI Accession #    NP_031548.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007522.2 [Other Products]
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 UniProt Primary Accession #    Q61337 [Other Products]
 UniProt Related Accession #    Q61337 [Other Products]
 Molecular Weight    22,080 Da
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 NCBI Official Full Name    bcl2 antagonist of cell death
 NCBI Official Synonym Full Names    BCL2-associated agonist of cell death
 NCBI Official Symbol    Bad [Similar Products]
 NCBI Official Synonym Symbols   
Bbc2; AI325008
[Similar Products]
 NCBI Protein Information    bcl2 antagonist of cell death; bcl-2-binding component 6; Bcl-associated death promoter; bcl-xL/Bcl-2-associated death promoter
 UniProt Protein Name    Bcl2 antagonist of cell death
 UniProt Synonym Protein Names   
Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter
 Protein Family    Bcl2-associated agonist of cell death
 UniProt Gene Name    Bad [Similar Products]
 UniProt Synonym Gene Names    Bbc6; BAD [Similar Products]
 UniProt Entry Name    BAD_MOUSE
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 UniProt Comments for BAD    BAD: a proapoptotic member of the Bcl-2 family. Displaces Bax from binding to Bcl-2 and Bcl-xL, resulting in cell death. Survival factors such as IL-3 can inhibit the apoptotic activity of Bad inducing the phosphorylation of Bad by Akt and p90RSK. 14-3-3 proteins bind phosphorylated Bad, inhibiting its binding to Bcl-2 and Bcl-xL. Phosphorylation by mitochondria-anchored PKA in the BH3 domain can block the dimerization of Bad and Bcl-xL.

Protein type: Apoptosis

Cellular Component: mitochondrial outer membrane; membrane; mitochondrion; cytoplasm; intracellular; cytosol

Molecular Function: protein kinase B binding; protein binding; protein heterodimerization activity; phospholipid binding; caspase activator activity; protein phosphatase binding; lipid binding; protein kinase binding; protein phosphatase 2B binding

Biological Process: apoptosis; positive regulation of proteolysis; positive regulation of apoptosis; positive regulation of caspase activity; regulation of caspase activity; cellular process regulating host cell cycle in response to virus; glucose homeostasis; positive regulation of apoptosis by virus; regulation of apoptosis; pore complex biogenesis; positive regulation of glucokinase activity; caspase activation; release of cytochrome c from mitochondria; cytokine and chemokine mediated signaling pathway; suppression by virus of host apoptosis; ADP metabolic process; positive regulation of insulin secretion; ATP metabolic process; cell proliferation; glucose catabolic process; induction of apoptosis via death domain receptors; DNA damage response, signal transduction resulting in induction of apoptosis; positive regulation of T cell differentiation; positive regulation of B cell differentiation; regulation of mitochondrial membrane permeability; positive regulation of epithelial cell proliferation
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 Research Articles on BAD    1. our study suggests that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BAD antibodyPathways associated with anti-BAD antibody
 Reference Product  PubMed Publications
 Bcl2l1 antibody  >533 publications with BAD and Bcl2l1
 Akt1 antibody  >239 publications with BAD and Akt1
 Bcl2 antibody  >167 publications with BAD and Bcl2
 Products by Pathway  Pathway Diagram
 AKT Phosphorylates Targets In The Cytosol Pathway antibodies  AKT Phosphorylates Targets In The Cytosol Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with anti-BAD antibodyOrgans/Tissues associated with anti-BAD antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4224 publications with BAD and Cardiovascular Diseases
 Neoplasms Antibodies  >4120 publications with BAD and Neoplasms
 Nervous System Diseases Antibodies  >3050 publications with BAD and Nervous System Diseases
 Heart Diseases Antibodies  >2438 publications with BAD and Heart Diseases
 Pain Antibodies  >1725 publications with BAD and Pain
 Brain Diseases Antibodies  >1468 publications with BAD and Brain Diseases
 Lung Diseases Antibodies  >1110 publications with BAD and Lung Diseases
 Inflammation Antibodies  >735 publications with BAD and Inflammation
 Hypertension Antibodies  >704 publications with BAD and Hypertension
 Necrosis Antibodies  >665 publications with BAD and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >4797 publications with BAD and Other
 Heart Antibodies  >2898 publications with BAD and Heart
 Bone Antibodies  >1683 publications with BAD and Bone
 Brain Antibodies  >1626 publications with BAD and Brain
 Lung Antibodies  >1007 publications with BAD and Lung
 Joint Antibodies  >982 publications with BAD and Joint
 Liver Antibodies  >873 publications with BAD and Liver
 Skin Antibodies  >752 publications with BAD and Skin
 Kidney Antibodies  >723 publications with BAD and Kidney
 Eye Antibodies  >462 publications with BAD and Eye
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