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anti-BAI1 antibody :: Rabbit anti-Human, mouse BAI1 Antibody

Scan QR to view Datasheet Catalog #    MBS003296 anti-BAI1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BAI1, Antibody

 Also Known As   

Rabbit BAI1 Antibody

 Product Gene Name   

anti-BAI1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 8; NC_000008.10 (143545377..143626368). Location: 8q24.3
 OMIM    602682
 3D Structure    ModBase 3D Structure for O14514
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-BAI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BAI1 antibody   

ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for BAI1. It may not necessarily be applicable to this product.
 NCBI GI #    111118994
 NCBI GeneID    575
 NCBI Accession #    NP_001693.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001702.2 [Other Products]
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 UniProt Primary Accession #    O14514 [Other Products]
 UniProt Related Accession #    O14514 [Other Products]
 Molecular Weight    173,501 Da
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 NCBI Official Full Name    brain-specific angiogenesis inhibitor 1
 NCBI Official Synonym Full Names    brain-specific angiogenesis inhibitor 1
 NCBI Official Symbol    BAI1 [Similar Products]
 NCBI Official Synonym Symbols   
GDAIF
[Similar Products]
 NCBI Protein Information    brain-specific angiogenesis inhibitor 1
 UniProt Protein Name    Brain-specific angiogenesis inhibitor 1
 Protein Family    BAI1-associated protein
 UniProt Gene Name    BAI1 [Similar Products]
 UniProt Entry Name    BAI1_HUMAN
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 NCBI Summary for BAI1    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
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 UniProt Comments for BAI1    BAI1: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane; intercellular junction

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; negative regulation of angiogenesis; axonogenesis; cell adhesion; signal transduction; peripheral nervous system development
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 Research Articles on BAI1    1. Proprotein convertases, primarily furin, activate latent matrix metalloproteinase-14, which then directly cleaves BAI1 to release the bioactive fragment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BAI1 antibodyPathways associated with anti-BAI1 antibody
 Reference Product  PubMed Publications
 MAGI1 antibody  >3 publications with BAI1 and MAGI1
 BAIAP2 antibody  >2 publications with BAI1 and BAIAP2
 PHYHIP antibody  >1 publications with BAI1 and PHYHIP
 Products by Pathway  Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
Diseases associated with anti-BAI1 antibodyOrgans/Tissues associated with anti-BAI1 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >18 publications with BAI1 and Brain Diseases
 Nervous System Diseases Antibodies  >16 publications with BAI1 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with BAI1 and Necrosis
 Kidney Diseases Antibodies  >2 publications with BAI1 and Kidney Diseases
 Inflammation Antibodies  >1 publications with BAI1 and Inflammation
 Disease Models, Animal Antibodies  >1 publications with BAI1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >47 publications with BAI1 and Brain
 Nerve Antibodies  >10 publications with BAI1 and Nerve
 Lung Antibodies  >4 publications with BAI1 and Lung
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