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anti-BCAS2 antibody :: Rabbit BCAS2 Antibody

Scan QR to view Datasheet Catalog #    MBS851853
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BCAS2, Antibody

 Also Known As   

BCAS2 Antibody

 Product Synonym Names    Pre-mRNA-splicing factor SPF27; Spliceosome-associated protein SPF 27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; BCAS2; DAM1
 Product Gene Name   

anti-BCAS2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605783
 3D Structure    ModBase 3D Structure for O75934
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    BCAS2 antibody detects endogenous levels of total BCAS2 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized peptide derived from C-terminal of human BCAS2.
 Pathway    Transcription
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-BCAS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-BCAS2 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-BCAS2 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-BCAS2 antibody    WB: 1:500~1:1000, ELISA: 1:5000
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 Testing Data of anti-BCAS2 antibody    Western blot analysis of extracts from HeLa cells, HepG2 cells, Huvec cells, A549 cells, K562 cells and Jurkat cells, using BCAS2 antibody.
anti-BCAS2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for BCAS2. It may not necessarily be applicable to this product.
 NCBI GI #    5031653
 NCBI GeneID    10286
 NCBI Accession #    NP_005863.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005872.2 [Other Products]
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 UniProt Primary Accession #    O75934 [Other Products]
 UniProt Secondary Accession #    Q6FGS0 [Other Products]
 UniProt Related Accession #    O75934 [Other Products]
 Molecular Weight    26,131 Da
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 NCBI Official Full Name    pre-mRNA-splicing factor SPF27
 NCBI Official Synonym Full Names    breast carcinoma amplified sequence 2
 NCBI Official Symbol    BCAS2 [Similar Products]
 NCBI Official Synonym Symbols   
DAM1; SPF27; Snt309
[Similar Products]
 NCBI Protein Information    pre-mRNA-splicing factor SPF27; breast carcinoma-amplified sequence 2; spliceosome-associated protein SPF 27; DNA amplified in mammary carcinoma 1 protein; spliceosome associated protein, amplified in breast cancer
 UniProt Protein Name    Pre-mRNA-splicing factor SPF27
 UniProt Synonym Protein Names   
Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27
 UniProt Gene Name    BCAS2 [Similar Products]
 UniProt Synonym Gene Names    DAM1 [Similar Products]
 UniProt Entry Name    SPF27_HUMAN
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 UniProt Comments for BCAS2    BCAS2: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Belongs to the SPF27 family.

Protein type: Spliceosome; Nuclear receptor co-regulator; RNA splicing; Nucleolus

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: nucleoplasm; spliceosome; DNA replication factor A complex; nucleolus; nucleus; cell junction

Molecular Function: protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; RNA splicing; gene expression
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Product References and Citations for anti-BCAS2 antibody

   Neubauer G., Nat. Genet. 20:46-50(1998).
Nagasaki K., Cancer Lett. 140:219-226(1999).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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 Research Articles on BCAS2    1. ERRbeta signalling leads to BCAS2-mediated blockage of the G1/S transition and inhibition of the epithelial to mesenchymal transition through FST-mediated regulation of E-cadherin
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BCAS2 antibodyPathways associated with anti-BCAS2 antibody
 Reference Product  PubMed Publications
 PLRG1 antibody  >2 publications with BCAS2 and PLRG1
 PRPF19 antibody  >2 publications with BCAS2 and PRPF19
 CDC5L antibody  >2 publications with BCAS2 and CDC5L
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome, 35S U5-snRNP Pathway antibodies  Spliceosome, 35S U5-snRNP Pathway Diagram
 Spliceosome, 35S U5-snRNP Pathway antibodies  Spliceosome, 35S U5-snRNP Pathway Diagram
 Spliceosome, Prp19/CDC5L Complex Pathway antibodies  Spliceosome, Prp19/CDC5L Complex Pathway Diagram
 Spliceosome, Prp19/CDC5L Complex Pathway antibodies  Spliceosome, Prp19/CDC5L Complex Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
Diseases associated with anti-BCAS2 antibodyOrgans/Tissues associated with anti-BCAS2 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with BCAS2 and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with BCAS2 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >1 publications with BCAS2 and Stomach
 Kidney Antibodies  >1 publications with BCAS2 and Kidney
 Brain Antibodies  >1 publications with BCAS2 and Brain
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