NP_001035758.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,665 Da
NCBI Official Full Name
bcl-2-like protein 12 isoform 3
NCBI Official Synonym Full Names
BCL2 like 12
NCBI Protein Information
bcl-2-like protein 12
UniProt Protein Name
Bcl-2-like protein 12
UniProt Synonym Protein Names
Bcl-2-related proline-rich protein
UniProt Synonym Gene Names
NCBI Summary for BCL2L12
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Product References and Citations for anti-BCL2L12 antibody
Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436]. Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258]. Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983]. Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258]. Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].
Research Articles on BCL2L12
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Disclaimer
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Diseases associated with anti-BCL2L12 antibody
Organs/Tissues associated with anti-BCL2L12 antibody
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