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anti-BHLHB3 antibody :: Rabbit BHLHB3 Antibody

Scan QR to view Datasheet Catalog #    MBS002550 anti-BHLHB3 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BHLHB3, Antibody

 Also Known As   

Rabbit BHLHB3 Antibody

 Product Gene Name   

anti-BHLHB3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (26272959..26278003, complement). Location: 12p12.1
 OMIM    606200
 3D Structure    ModBase 3D Structure for Q9C0J9
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-BHLHB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BHLHB3 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for BHLHB3. It may not necessarily be applicable to this product.
 NCBI GI #    13540521
 NCBI GeneID    79365
 NCBI Accession #    NP_110389.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030762.2 [Other Products]
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 UniProt Primary Accession #    Q9C0J9 [Other Products]
 UniProt Secondary Accession #    A2I2N8 [Other Products]
 UniProt Related Accession #    Q9C0J9 [Other Products]
 Molecular Weight    50,498 Da
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 NCBI Official Full Name    class E basic helix-loop-helix protein 41
 NCBI Official Synonym Full Names    basic helix-loop-helix family, member e41
 NCBI Official Symbol    BHLHE41 [Similar Products]
 NCBI Official Synonym Symbols   
DEC2; hDEC2; BHLHB3; SHARP1
[Similar Products]
 NCBI Protein Information    class E basic helix-loop-helix protein 41; enhancer-of-split and hairy-related protein 1; differentially expressed in chondrocytes protein 2; basic helix-loop-helix domain containing, class B, 3
 UniProt Protein Name    Class E basic helix-loop-helix protein 41
 UniProt Synonym Protein Names   
Class B basic helix-loop-helix protein 3; bHLHb3; Differentially expressed in chondrocytes protein 2; hDEC2; Enhancer-of-split and hairy-related protein 1
 UniProt Gene Name    BHLHE41 [Similar Products]
 UniProt Synonym Gene Names    BHLHB3; DEC2; SHARP1; bHLHe41; bHLHb3; hDEC2; SHARP-1 [Similar Products]
 UniProt Entry Name    BHE41_HUMAN
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 NCBI Summary for BHLHB3    This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, May 2010]
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 UniProt Comments for BHLHB3    BHLHB3: May be a transcriptional repressor that represses both basal and activated transcription. Homodimerize.

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; MRF binding; protein binding; protein homodimerization activity; protein heterodimerization activity; histone deacetylase binding; bHLH transcription factor binding; transcription corepressor activity

Biological Process: circadian rhythm; transcription from RNA polymerase II promoter; cell proliferation; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; cell differentiation

Disease: Short Sleeper
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 Research Articles on BHLHB3    1. DEC2 regulates apoptosis in oral cancer cells via regulation of pro-apoptotic factor Bim expression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BHLHB3 antibodyPathways associated with anti-BHLHB3 antibody
 Reference Product  PubMed Publications
 BHLHE40 antibody  >11 publications with BHLHB3 and BHLHE40
 MYOD1 antibody  >1 publications with BHLHB3 and MYOD1
 Products by Pathway  Pathway Diagram
 BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway antibodies  BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
Diseases associated with anti-BHLHB3 antibodyOrgans/Tissues associated with anti-BHLHB3 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with BHLHB3 and Breast Neoplasms
 Nervous System Diseases Antibodies  >4 publications with BHLHB3 and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >3 publications with BHLHB3 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >2 publications with BHLHB3 and Lung Neoplasms
 Endometrial Neoplasms Antibodies  >1 publications with BHLHB3 and Endometrial Neoplasms
 Hypertension Antibodies  >1 publications with BHLHB3 and Hypertension
 Depressive Disorder Antibodies  >1 publications with BHLHB3 and Depressive Disorder
 Cardiovascular Diseases Antibodies  >1 publications with BHLHB3 and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with BHLHB3 and Hyperplasia
 Inflammation Antibodies  >1 publications with BHLHB3 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with BHLHB3 and Liver
 Kidney Antibodies  >3 publications with BHLHB3 and Kidney
 Vascular Antibodies  >3 publications with BHLHB3 and Vascular
 Brain Antibodies  >3 publications with BHLHB3 and Brain
 Lung Antibodies  >2 publications with BHLHB3 and Lung
 Muscle Antibodies  >2 publications with BHLHB3 and Muscle
 Heart Antibodies  >1 publications with BHLHB3 and Heart
 Connective Tissue Antibodies  >1 publications with BHLHB3 and Connective Tissue
 Lymph Node Antibodies  >1 publications with BHLHB3 and Lymph Node
 Eye Antibodies  >1 publications with BHLHB3 and Eye
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