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anti-BNIP2 antibody :: Rabbit anti-Human, Mouse BNIP2 Antibody

Scan QR to view Datasheet Catalog #    MBS851956
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BNIP2, Antibody

 Also Known As   

BNIP2 Antibody

 Product Synonym Names    BCL2/adenovirus E1B 19-kDa protein-interacting 2; BCL2/adenovirus E1B 19kD interacting 2; BCL2/adenovirus E1B 19kD-interacting 2; BCL2/adenovirus E1B 19kDa interacting 2; BNIP-2; NIP2
 Product Gene Name   

anti-BNIP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603292
 3D Structure    ModBase 3D Structure for Q12982
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 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    BNIP2 antibody detects endogenous levels of total BNIP2 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from C-terminal of human BNIP2.
 Pathway    Cancer/Apoptosis
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-BNIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-BNIP2 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-BNIP2 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-BNIP2 antibody    WB: 1:500~1:1000, ELISA: 1:40000
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 Testing Data of anti-BNIP2 antibody    Western blot analysis of extracts from Jurkat cells, using BNIP2 antibody.
anti-BNIP2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for BNIP2. It may not necessarily be applicable to this product.
 NCBI GI #    168480080
 NCBI GeneID    663
 NCBI Accession #    NP_004321.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004330.2 [Other Products]
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 UniProt Primary Accession #    Q12982 [Other Products]
 UniProt Secondary Accession #    B4DS94 [Other Products]
 UniProt Related Accession #    Q12982 [Other Products]
 Molecular Weight    43,135 Da
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 NCBI Official Full Name    BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
 NCBI Official Synonym Full Names    BCL2/adenovirus E1B 19kDa interacting protein 2
 NCBI Official Symbol    BNIP2 [Similar Products]
 NCBI Official Synonym Symbols   
NIP2; BNIP-2
[Similar Products]
 NCBI Protein Information    BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
 UniProt Protein Name    BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
 Protein Family    BCL2/adenovirus E1B 19 kDa protein-interacting protein
 UniProt Gene Name    BNIP2 [Similar Products]
 UniProt Synonym Gene Names    NIP2 [Similar Products]
 UniProt Entry Name    BNIP2_HUMAN
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 NCBI Summary for BNIP2    This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. [provided by RefSeq, Mar 2011]
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 UniProt Comments for BNIP2    BNIP2: Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; cytosol

Molecular Function: identical protein binding; protein binding; calcium ion binding; GTPase activator activity

Biological Process: muscle cell differentiation; apoptosis; positive regulation of muscle cell differentiation; negative regulation of apoptosis; positive regulation of GTPase activity
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Product References and Citations for anti-BNIP2 antibody

   Boyd J.M., Cell 79:341-351(1994).
Rieder M.J., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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 Research Articles on BNIP2    1. Data imply that SIRT1 may mediate MPP(+)-induced cytotoxicity, possibly through the regulation of BNIP2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BNIP2 antibodyPathways associated with anti-BNIP2 antibody
 Reference Product  PubMed Publications
 CDC42 antibody  >8 publications with BNIP2 and CDC42
 BCL2 antibody  >5 publications with BNIP2 and BCL2
 FGFR1 antibody  >1 publications with BNIP2 and FGFR1
 Products by Pathway  Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Myogenesis Pathway antibodies  Myogenesis Pathway Diagram
Diseases associated with anti-BNIP2 antibodyOrgans/Tissues associated with anti-BNIP2 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with BNIP2 and Necrosis
 Brain Diseases Antibodies  >1 publications with BNIP2 and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with BNIP2 and Disease Models, Animal
 Immune System Diseases Antibodies  >1 publications with BNIP2 and Immune System Diseases
 Inflammation Antibodies  >1 publications with BNIP2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with BNIP2 and Brain
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