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anti-BNP antibody :: Mouse anti-Human BNP Antibody

Scan QR to view Datasheet Catalog #    MBS355823 anti-BNP antibody
Unit / Price
1 mg  /  $420 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BNP, Antibody

★Popular Item★
 Also Known As   

Anti-BNP Antibody (Detection Ab)

 Product Synonym Names    Brain natriuretic peptide, BNP mAb (Mouse anti-human, clone # 2D6)-Capture Ab
 Product Gene Name   

anti-BNP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M31776 Genomic DNA
 3D Structure    ModBase 3D Structure for P16860
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 Isotype    IgG2b
 Clone Number    2D6
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    >95% by HPLC & SDS-PAGE
 Form/Format    Liquid
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.
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 Preparation and Storage    Aliquot and store at -20░C for long term (at least one year).

Avoid repeated freeze and thaw cycles.
 Other Notes    Small volumes of anti-BNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BNP antibody

   Background: Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide or natriuretic peptide B) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). BNP is secreted attached to a 76ľamino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB.
 Applications Tested/Suitable for anti-BNP antibody   

ELISA (EIA), Chemiluminescence Immunoassays (CLIA), Flow Fluorenscence Immunmicrobeads Assay (FFIA)

 Application Notes for anti-BNP antibody    Other applications have not been tested

The optimal dilutions should not be determined by end user.

Matched antibody pair:

Capture Ab: BNP: mAb (clone #B4)
Detection Ab: BNP mAb ( clone#2D6)
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NCBI/Uniprot data below describe general gene information for BNP. It may not necessarily be applicable to this product.
 NCBI GI #    4505433
 NCBI GeneID    4879
 NCBI Accession #    NP_002512.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002521.2 [Other Products]
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 UniProt Primary Accession #    P16860 [Other Products]
 UniProt Secondary Accession #    Q6FGY0; Q9P2Q7; B0ZBE9 [Other Products]
 UniProt Related Accession #    P16860 [Other Products]
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 NCBI Official Full Name    natriuretic peptides B preproprotein
 NCBI Official Synonym Full Names    natriuretic peptide B
 NCBI Official Symbol    NPPB [Similar Products]
 NCBI Official Synonym Symbols   
BNP
[Similar Products]
 NCBI Protein Information    natriuretic peptides B
 UniProt Protein Name    Natriuretic peptides B
 UniProt Synonym Protein Names   
Gamma-brain natriuretic peptide
 UniProt Gene Name    NPPB [Similar Products]
 UniProt Synonym Gene Names    BNP(1-32); BNP-32 [Similar Products]
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 NCBI Summary for BNP    This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
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 UniProt Comments for BNP    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
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Product References and Citations for anti-BNP antibody

   1. Ziskoven D, Forssmann WG, Holthausen U, Menz G, Addicks K, Rippegater G (1989). "Calcium Calmodulin antagonists Influences the release of Cardiodilatin/ANP from Atrial Cardiocytes". In Kaufmann W, Wambach G. Handbook Endocrinology of the Heart. Berlin: Verlag: Springer. pp. 233-4.
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 Research Articles on BNP    1. Higher blood levels of NT-proBNP was associated with incident cognitive impairments.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BNP antibodyPathways associated with anti-BNP antibody
 Reference Product  PubMed Publications
 NPPA antibody  >69 publications with BNP and NPPA
 NPPC antibody  >10 publications with BNP and NPPC
 NPR3 antibody  >10 publications with BNP and NPR3
 NPR1 antibody  >9 publications with BNP and NPR1
 NPR2 antibody  >7 publications with BNP and NPR2
 ACE antibody  >3 publications with BNP and ACE
 TNNI3 antibody  >2 publications with BNP and TNNI3
 ATF2 antibody  >1 publications with BNP and ATF2
 Products by Pathway  Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 CGMP-PKG Signaling Pathway antibodies  CGMP-PKG Signaling Pathway Diagram
 CGMP-PKG Signaling Pathway antibodies  CGMP-PKG Signaling Pathway Diagram
Diseases associated with anti-BNP antibodyOrgans/Tissues associated with anti-BNP antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >153 publications with BNP and Fibrosis
 Cardiovascular Diseases Antibodies  >103 publications with BNP and Cardiovascular Diseases
 Heart Diseases Antibodies  >61 publications with BNP and Heart Diseases
 Heart Failure Antibodies  >39 publications with BNP and Heart Failure
 Hypertension Antibodies  >35 publications with BNP and Hypertension
 Hypertrophy Antibodies  >34 publications with BNP and Hypertrophy
 Cardiomegaly Antibodies  >20 publications with BNP and Cardiomegaly
 Edema Antibodies  >19 publications with BNP and Edema
 Cardiomyopathies Antibodies  >18 publications with BNP and Cardiomyopathies
 Inflammation Antibodies  >17 publications with BNP and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >151 publications with BNP and Kidney
 Heart Antibodies  >125 publications with BNP and Heart
 Lung Antibodies  >69 publications with BNP and Lung
 Liver Antibodies  >44 publications with BNP and Liver
 Pancreas Antibodies  >29 publications with BNP and Pancreas
 Embryonic Tissue Antibodies  >23 publications with BNP and Embryonic Tissue
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