NP_004325.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,326 Da
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
NCBI Official Synonym Full Names
bone marrow stromal cell antigen 1
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Synonym Protein Names
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157
UniProt Synonym Gene Names
NCBI Summary for BST1
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
UniProt Comments for BST1
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Product References and Citations for anti-BST1 antibody
Kaisho T., Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994). Kalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 434:724-731(2005).
Research Articles on BST1
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Pathways associated with anti-BST1 antibody
Diseases associated with anti-BST1 antibody
Organs/Tissues associated with anti-BST1 antibody
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