Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow Bmi1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Interferon-gamma (k9IFNG) Recombinant Protein
 • Alpha-S2-casein-like A (Csn1s2a) Recombinant Protein
 • MKI67 Antibody
 • Four and a half LIM domains protein 1 (FHL1) Recombinant Protein
 • DESMIN Antibody
 • A-769662 Biochemical
 • Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) ELISA Kit
 • Interleukin 6 (IL-6) ELISA Kit
 • soluble Cluster of differentiation 86, sCD86 (B72-sCD86) ELISA Kit
 • MT-ND4 siRNA
 • Death-associated protein 1 (DAP1) Recombinant Protein
 • PSA Antibody
 • Tissue Inhibitors of Metalloproteinase 4 (TIMP-4) ELISA Kit
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-Bmi1 antibody :: anti-Human Bmi1 Antibody

Scan QR to view Datasheet Catalog #    MBS850829
Testing Data
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bmi1, Antibody

 Also Known As   

Bmi1 Antibody

 Product Synonym Names    Mouse monoclonal IgG to Bmi1
 Product Gene Name   

anti-Bmi1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    164831
 3D Structure    ModBase 3D Structure for P35226
Section Bar
 Species Reactivity    Human
Section Bar
 Purity/Purification    Protein G-Sepharose affinity purified
 Form/Format    Liquid
Section Bar
 Immunogen    Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
 Preservative    0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
 Cellular Localization    Nucleus
Section Bar
 Preparation and Storage    Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-Bmi1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-Bmi1 antibody

   The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
 Product Categories/Family for anti-Bmi1 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-Bmi1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Bmi1 antibody    ELISA: 1:5000-1:20000
WB: 1:100-1:2000
Section Bar
 Testing Data of anti-Bmi1 antibody    Bmi1 antibody at 1/500 dilution. Hela whole cell lysate at 40ug/Lane. Predicted band size: 37Kda. Observed band size: 37Kda.
anti-Bmi1 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Bmi1. It may not necessarily be applicable to this product.
 NCBI GI #    27883842
 NCBI GeneID    648
 NCBI Accession #    NP_005171.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_005180.5 [Other Products]
Section Bar
 UniProt Primary Accession #    P35226 [Other Products]
 UniProt Secondary Accession #    Q16030; Q5T8Z3; Q96F37 [Other Products]
 UniProt Related Accession #    P35226 [Other Products]
 Molecular Weight    36,949 Da
Table BarTOPTable Bar
 NCBI Official Full Name    polycomb complex protein BMI-1
 NCBI Official Synonym Full Names    BMI1 proto-oncogene, polycomb ring finger
 NCBI Official Symbol    BMI1 [Similar Products]
 NCBI Official Synonym Symbols   
PCGF4; RNF51; FLVI2/BMI1; flvi-2/bmi-1
[Similar Products]
 NCBI Protein Information    polycomb complex protein BMI-1
 UniProt Protein Name    Polycomb complex protein BMI-1
 UniProt Synonym Protein Names   
Polycomb group RING finger protein 4; RING finger protein 51
 Protein Family    Polycomb complex protein
 UniProt Gene Name    BMI1 [Similar Products]
 UniProt Synonym Gene Names    PCGF4; RNF51 [Similar Products]
Section Bar
 NCBI Summary for Bmi1    This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
Section Bar
 UniProt Comments for Bmi1    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373). The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed:21772249, PubMed:25355358). In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:26151332, PubMed:21772249).
Table BarTOPTable Bar
 Research Articles on Bmi1    1. These preclinical data in mouse models and human cells provide a strong rationale for the development of pharmacological approaches to target BMI1-mediated mitochondrial regulation and protection from DNA damage to sustain the regenerative potential of the skeletal muscle in conditions of chronic muscle wasting.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-Bmi1 antibodyPathways associated with anti-Bmi1 antibody
 Reference Product  PubMed Publications
 RING1 antibody  >36 publications with Bmi1 and RING1
 RNF2 antibody  >19 publications with Bmi1 and RNF2
 CBX4 antibody  >15 publications with Bmi1 and CBX4
 CBX2 antibody  >12 publications with Bmi1 and CBX2
 PHC1 antibody  >9 publications with Bmi1 and PHC1
 CBX7 antibody  >8 publications with Bmi1 and CBX7
 CBX8 antibody  >5 publications with Bmi1 and CBX8
 PHC2 antibody  >4 publications with Bmi1 and PHC2
 PHC3 antibody  >2 publications with Bmi1 and PHC3
 CBX6 antibody  >1 publications with Bmi1 and CBX6
 Products by Pathway  Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Oxidative Stress Induced Senescence Pathway antibodies  Oxidative Stress Induced Senescence Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies  Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram
Organs/Tissues associated with anti-Bmi1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >90 publications with Bmi1 and Brain
 Lung Antibodies  >53 publications with Bmi1 and Lung
 Embryonic Tissue Antibodies  >38 publications with Bmi1 and Embryonic Tissue
 Skin Antibodies  >37 publications with Bmi1 and Skin
 Muscle Antibodies  >19 publications with Bmi1 and Muscle
 Eye Antibodies  >17 publications with Bmi1 and Eye
 Kidney Antibodies  >12 publications with Bmi1 and Kidney
 Heart Antibodies  >9 publications with Bmi1 and Heart
 Testis Antibodies  >5 publications with Bmi1 and Testis
 Placenta Antibodies  >4 publications with Bmi1 and Placenta
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions