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anti-C1S antibody :: anti-Human C1S Antibody

Scan QR to view Datasheet Catalog #    MBS851785
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C1S, Antibody

★Popular Item★
 Also Known As   

C1S Antibody

 Product Synonym Names    28S ribosomal protein S7,mitochondrial; S7mt; MRP-S7; bMRP27a; bMRP-27a
 Product Gene Name   

anti-C1S antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    120580
 3D Structure    ModBase 3D Structure for P09871
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 Species Reactivity    Human
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 Specificity    C1S antibody detects endogenous levels of total C1S protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human C1S.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-C1S antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-C1S antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-C1S antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-C1S antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000
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 Testing Data of anti-C1S antibody    Peptide-+
anti-C1S antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-C1S antibody    Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using C1S antibody. Western blot analysis of extracts from Jurkat cells and COLO cells, using C1S antibody.
anti-C1S antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for C1S. It may not necessarily be applicable to this product.
 NCBI GI #    1098385908
 NCBI GeneID    716
 NCBI Accession #    NP_001333779.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001346850.1 [Other Products]
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 UniProt Primary Accession #    P09871 [Other Products]
 UniProt Secondary Accession #    Q9UCU7; Q9UCU8; Q9UCU9; Q9UCV0; Q9UCV1; Q9UCV2; Q9UCV3; Q9UCV4; Q9UCV5; Q9UM14; D3DUT4 [Other Products]
 UniProt Related Accession #    P09871 [Other Products]
 Molecular Weight    76,684 Da
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 NCBI Official Full Name    complement C1s subcomponent isoform 2
 NCBI Official Synonym Full Names    complement C1s
 NCBI Official Symbol    C1S [Similar Products]
 NCBI Official Synonym Symbols   
EDSPD2
[Similar Products]
 NCBI Protein Information    complement C1s subcomponent
 UniProt Protein Name    Complement C1s subcomponent
 UniProt Synonym Protein Names   
C1 esterase; Complement component 1 subcomponent s
 UniProt Gene Name    C1S [Similar Products]
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 NCBI Summary for C1S    This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
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 UniProt Comments for C1S    C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
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Product References and Citations for anti-C1S antibody

   McKinnon C.M., Eur. J. Biochem. 169:547-553(1987). Tosi M., Biochemistry 26:8516-8524(1987). Kusumoto H., Proc. Natl. Acad. Sci. U.S.A. 85:7307-7311(1988).
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 Research Articles on C1S    1. The serine protease domains of C1r and C1s are at the periphery of the C1r2s2 tetramer both when alone or within the nonactivated C1 complex. The C1 complex adopts a conformation incompatible with intramolecular activation of C1. Instead, intermolecular proteolytic activation between neighboring C1 complexes bound to a complement-activating surface occurs. Many structurally unrelated molecular patterns can activate C1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-C1S antibodyPathways associated with anti-C1S antibody
 Reference Product  PubMed Publications
 C1R antibody  >647 publications with C1S and C1R
 SERPING1 antibody  >166 publications with C1S and SERPING1
 C4B antibody  >73 publications with C1S and C4B
 C4A antibody  >31 publications with C1S and C4A
 CRP antibody  >12 publications with C1S and CRP
 C1QB antibody  >8 publications with C1S and C1QB
 C1QA antibody  >5 publications with C1S and C1QA
 C1QC antibody  >5 publications with C1S and C1QC
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Activation Pathway antibodies  Complement Activation Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with anti-C1S antibodyOrgans/Tissues associated with anti-C1S antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >145 publications with C1S and Cardiovascular Diseases
 Autoimmune Diseases Antibodies  >99 publications with C1S and Autoimmune Diseases
 Inflammation Antibodies  >90 publications with C1S and Inflammation
 Edema Antibodies  >46 publications with C1S and Edema
 Kidney Diseases Antibodies  >31 publications with C1S and Kidney Diseases
 Necrosis Antibodies  >25 publications with C1S and Necrosis
 Liver Diseases Antibodies  >23 publications with C1S and Liver Diseases
 Heart Diseases Antibodies  >17 publications with C1S and Heart Diseases
 Weight Loss Antibodies  >16 publications with C1S and Weight Loss
 Anemia Antibodies  >16 publications with C1S and Anemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >340 publications with C1S and Blood
 Bone Antibodies  >80 publications with C1S and Bone
 Vascular Antibodies  >66 publications with C1S and Vascular
 Liver Antibodies  >60 publications with C1S and Liver
 Skin Antibodies  >44 publications with C1S and Skin
 Kidney Antibodies  >37 publications with C1S and Kidney
 Brain Antibodies  >34 publications with C1S and Brain
 Muscle Antibodies  >26 publications with C1S and Muscle
 Embryonic Tissue Antibodies  >23 publications with C1S and Embryonic Tissue
 Heart Antibodies  >21 publications with C1S and Heart
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