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anti-CD133 antibody :: Rabbit CD133 Antibody

Scan QR to view Datasheet Catalog #    MBS8502036
Western Blot (WB)
Unit / Price
0.1 mL  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD133, Antibody

★Popular Item★
 Also Known As   

CD133 Antibody

 Product Synonym Names    CD133; PROM1; PROM1 1; MSTP061; MCDR2; PROM1 1; 6; 7
 Product Gene Name   

anti-CD133 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603786
 3D Structure    ModBase 3D Structure for O43490
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity purification
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 Immunogen    C term-peptide of human CD133
 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-CD133 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD133 antibody

   This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
 Product Categories/Family for anti-CD133 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CD133 antibody   

Western Blot (WB)

 Application Notes for anti-CD133 antibody    WB: 1:500-1:2000
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 Western Blot (WB) of anti-CD133 antibody    Western blot analysis of extractsofSW620cells, using CD133 antibody.
anti-CD133 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CD133. It may not necessarily be applicable to this product.
 NCBI GI #    224994189
 NCBI GeneID    8842
 NCBI Accession #    NP_001139319.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145847.1 [Other Products]
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 UniProt Primary Accession #    O43490 [Other Products]
 UniProt Secondary Accession #    Q6SV49; Q6SV50; Q6SV51; Q6SV52; Q6SV53; Q96EN6 [Other Products]
 UniProt Related Accession #    O43490 [Other Products]
 Molecular Weight    97kDa
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 NCBI Official Full Name    prominin-1 isoform 2
 NCBI Official Synonym Full Names    prominin 1
 NCBI Official Symbol    PROM1 [Similar Products]
 NCBI Official Synonym Symbols   
RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
[Similar Products]
 NCBI Protein Information    prominin-1
 UniProt Protein Name    Prominin-1
 UniProt Synonym Protein Names   
Antigen AC133; Prominin-like protein 1; CD_antigen: CD133
 UniProt Gene Name    PROM1 [Similar Products]
 UniProt Synonym Gene Names    PROML1 [Similar Products]
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 NCBI Summary for CD133    This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for CD133    May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
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 Research Articles on CD133    1. glioma cells expressing CD133 are capable of modulating tumor microenvironment through the IL-1beta signaling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD133 antibodyPathways associated with anti-CD133 antibody
 Reference Product  PubMed Publications
 CD44 antibody  >8 publications with CD133 and CD44
 CD34 antibody  >3 publications with CD133 and CD34
 KDR antibody  >2 publications with CD133 and KDR
 HIF1A antibody  >2 publications with CD133 and HIF1A
 CDHR1 antibody  >2 publications with CD133 and CDHR1
 NES antibody  >1 publications with CD133 and NES
 RET antibody  >1 publications with CD133 and RET
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with anti-CD133 antibodyOrgans/Tissues associated with anti-CD133 antibody
 Disease Name  Pubmed Publications
 Colorectal Neoplasms Antibodies  >12 publications with CD133 and Colorectal Neoplasms
 Carcinoma Antibodies  >9 publications with CD133 and Carcinoma
 Adenocarcinoma Antibodies  >6 publications with CD133 and Adenocarcinoma
 Glioblastoma Antibodies  >6 publications with CD133 and Glioblastoma
 Colonic Neoplasms Antibodies  >5 publications with CD133 and Colonic Neoplasms
 Disease Models, Animal Antibodies  >5 publications with CD133 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with CD133 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >3 publications with CD133 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with CD133 and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with CD133 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >16 publications with CD133 and Eye
 Brain Antibodies  >14 publications with CD133 and Brain
 Liver Antibodies  >10 publications with CD133 and Liver
 Nerve Antibodies  >5 publications with CD133 and Nerve
 Intestine Antibodies  >4 publications with CD133 and Intestine
 Embryonic Tissue Antibodies  >4 publications with CD133 and Embryonic Tissue
 Lung Antibodies  >3 publications with CD133 and Lung
 Stomach Antibodies  >2 publications with CD133 and Stomach
 Testis Antibodies  >2 publications with CD133 and Testis
 Mammary Gland Antibodies  >1 publications with CD133 and Mammary Gland
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