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anti-CD153 antibody :: Rabbit anti-Human, mouse CD153 Antibody

Scan QR to view Datasheet Catalog #    MBS001310 anti-CD153 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD153, Antibody

 Also Known As   

Rabbit CD153 Antibody

 Product Gene Name   

anti-CD153 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (117655623..117692875, complement). Location: 9q33
 OMIM    603875
 3D Structure    ModBase 3D Structure for P32971
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-CD153 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CD153 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for CD153. It may not necessarily be applicable to this product.
 NCBI GI #    4507607
 NCBI GeneID    944
 NCBI Accession #    NP_001235.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001244.3 [Other Products]
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 UniProt Primary Accession #    P32971 [Other Products]
 UniProt Secondary Accession #    O43404 [Other Products]
 UniProt Related Accession #    P32971 [Other Products]
 Molecular Weight    26,017 Da
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 NCBI Official Full Name    tumor necrosis factor ligand superfamily member 8 isoform 1
 NCBI Official Synonym Full Names    tumor necrosis factor (ligand) superfamily, member 8
 NCBI Official Symbol    TNFSF8 [Similar Products]
 NCBI Official Synonym Symbols   
CD153; CD30L; CD30LG
[Similar Products]
 NCBI Protein Information    tumor necrosis factor ligand superfamily member 8; CD30-L; CD30 ligand; CD153 antigen; CD30 antigen ligand
 UniProt Protein Name    Tumor necrosis factor ligand superfamily member 8
 UniProt Synonym Protein Names   
CD30 ligand
 UniProt Gene Name    TNFSF8 [Similar Products]
 UniProt Synonym Gene Names    CD30L; CD30LG; CD30-L [Similar Products]
 UniProt Entry Name    TNFL8_HUMAN
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 NCBI Summary for CD153    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for CD153    TNFSF8: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells. Belongs to the tumor necrosis factor family.

Protein type: Apoptosis; Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q33

Cellular Component: extracellular space; integral to plasma membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; CD8-positive, alpha-beta T cell differentiation; defense response to Gram-positive bacterium; cell-cell signaling; apoptosis; immune response; positive regulation of transcription from RNA polymerase II promoter; signal transduction
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 Research Articles on CD153    1. a novel and unexpected role for CD30/CD30L that contributes to proinflammatory immune responses
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD153 antibodyPathways associated with anti-CD153 antibody
 Reference Product  PubMed Publications
 TNFRSF8 antibody  >2 publications with CD153 and TNFRSF8
 ANG antibody  >1 publications with CD153 and ANG
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-CD153 antibodyOrgans/Tissues associated with anti-CD153 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >55 publications with CD153 and Necrosis
 Neoplasms Antibodies  >52 publications with CD153 and Neoplasms
 Leukemia Antibodies  >18 publications with CD153 and Leukemia
 Inflammation Antibodies  >8 publications with CD153 and Inflammation
 Carcinoma Antibodies  >5 publications with CD153 and Carcinoma
 Skin Neoplasms Antibodies  >4 publications with CD153 and Skin Neoplasms
 Drug Toxicity Antibodies  >3 publications with CD153 and Drug Toxicity
 Lung Neoplasms Antibodies  >3 publications with CD153 and Lung Neoplasms
 Multiple Myeloma Antibodies  >3 publications with CD153 and Multiple Myeloma
 Breast Neoplasms Antibodies  >2 publications with CD153 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >64 publications with CD153 and Blood
 Lung Antibodies  >6 publications with CD153 and Lung
 Pancreas Antibodies  >1 publications with CD153 and Pancreas
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