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anti-CD2 - CD20 antibody :: Mouse anti-Human CD2 - CD20 Antibody

Scan QR to view Datasheet Catalog #    MBS396243 anti-CD2 - CD20 antibody
Unit / Price
50 Tests  /  $280 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD2 - CD20, Antibody

★Popular Item★
 Also Known As   

CD2 FITC - CD20 PE

 Product Gene Name   

anti-CD2 - CD20 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (117297086..117311851). Location: 1p13.1
 OMIM    186990
 3D Structure    ModBase 3D Structure for P06729
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 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Protein A/G Chromatography
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 Immunogen    CD2=Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with t lymphocytes activated by mixed lymphocyte culture.CD20=Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with the LB lymphoblastoid cell line.
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 Preparation and Storage    Store at 4 degree C.
 Other Notes    Small volumes of anti-CD2 - CD20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CD2 - CD20 antibody    Bi-Test Reagents (FITC/RPE); Bi-Test(tm) Reagents
 Applications Tested/Suitable for anti-CD2 - CD20 antibody   

Flow Cytometry (FC/FACS)

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NCBI/Uniprot data below describe general gene information for CD2 - CD20. It may not necessarily be applicable to this product.
 NCBI GI #    156071472
 NCBI GeneID    914
 NCBI Accession #    NP_001758.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001767.3 [Other Products]
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 UniProt Primary Accession #    P06729 [Other Products]
 UniProt Secondary Accession #    Q96TE5 [Other Products]
 UniProt Related Accession #    P06729 [Other Products]
 Molecular Weight    39,448 Da
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 NCBI Official Full Name    T-cell surface antigen CD2
 NCBI Official Synonym Full Names    CD2 molecule
 NCBI Official Symbol    CD2 [Similar Products]
 NCBI Official Synonym Symbols   
T11; SRBC; LFA-2
[Similar Products]
 NCBI Protein Information    T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
 UniProt Protein Name    T-cell surface antigen CD2
 UniProt Synonym Protein Names   
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5
 UniProt Gene Name    CD2 [Similar Products]
 UniProt Synonym Gene Names    SRBC [Similar Products]
 UniProt Entry Name    CD2_HUMAN
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 NCBI Summary for CD2 - CD20    CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
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 UniProt Comments for CD2 - CD20    Function: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Subunit structure: Interacts with CD2AP

By similarity. Interacts with PSTPIP1. Ref.11

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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 Research Articles on CD2 - CD20    1. CD2-CD58/48 receptor-ligand interaction promotes and is required for nanotube formation in human natural killer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD2 - CD20 antibodyPathways associated with anti-CD2 - CD20 antibody
 Reference Product  PubMed Publications
 CD58 antibody  >414 publications with CD2 - CD20 and CD58
 PTPRC antibody  >341 publications with CD2 - CD20 and PTPRC
 CD48 antibody  >145 publications with CD2 - CD20 and CD48
 CD2AP antibody  >138 publications with CD2 - CD20 and CD2AP
 LCK antibody  >79 publications with CD2 - CD20 and LCK
 SH3KBP1 antibody  >18 publications with CD2 - CD20 and SH3KBP1
 CD2BP2 antibody  >12 publications with CD2 - CD20 and CD2BP2
 CD8A antibody  >3 publications with CD2 - CD20 and CD8A
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-CD2 - CD20 antibodyOrgans/Tissues associated with anti-CD2 - CD20 antibody
 Disease Name  Pubmed Publications
 Lymphoma Antibodies  >822 publications with CD2 - CD20 and Lymphoma
 Drug Toxicity Antibodies  >512 publications with CD2 - CD20 and Drug Toxicity
 Necrosis Antibodies  >305 publications with CD2 - CD20 and Necrosis
 Lymphoma, B-Cell Antibodies  >234 publications with CD2 - CD20 and Lymphoma, B-Cell
 Inflammation Antibodies  >225 publications with CD2 - CD20 and Inflammation
 Kidney Diseases Antibodies  >139 publications with CD2 - CD20 and Kidney Diseases
 Liver Diseases Antibodies  >122 publications with CD2 - CD20 and Liver Diseases
 Anemia Antibodies  >98 publications with CD2 - CD20 and Anemia
 Vascular Diseases Antibodies  >97 publications with CD2 - CD20 and Vascular Diseases
 Fever Antibodies  >97 publications with CD2 - CD20 and Fever
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4588 publications with CD2 - CD20 and Blood
 Bone Antibodies  >744 publications with CD2 - CD20 and Bone
 Muscle Antibodies  >540 publications with CD2 - CD20 and Muscle
 Kidney Antibodies  >468 publications with CD2 - CD20 and Kidney
 Thymus Antibodies  >435 publications with CD2 - CD20 and Thymus
 Lymph Node Antibodies  >378 publications with CD2 - CD20 and Lymph Node
 Heart Antibodies  >303 publications with CD2 - CD20 and Heart
 Spleen Antibodies  >271 publications with CD2 - CD20 and Spleen
 Intestine Antibodies  >250 publications with CD2 - CD20 and Intestine
 Lung Antibodies  >179 publications with CD2 - CD20 and Lung
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