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anti-CD3 - CD19 antibody :: Mouse anti-Human CD3 - CD19 Antibody

Scan QR to view Datasheet Catalog #    MBS396225 anti-CD3 - CD19 antibody
Unit / Price
  DISCONTINUED
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD3 - CD19, Antibody

 Also Known As   

CD3 FITC - CD19 PE

 Product Gene Name   

anti-CD3 - CD19 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 11; NC_000011.9 (118175295..118186890). Location: 11q23
 OMIM    186830
 3D Structure    ModBase 3D Structure for P07766
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 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Protein A/G Chromatography
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 Immunogen    CD3=Derived from the hybridization of mouse NS-1 myeloma celss with spleen cells from BALB/c mice immunized with human thymocytes.
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 Preparation and Storage    Store at 4 degree C.
 Other Notes    Small volumes of anti-CD3 - CD19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CD3 - CD19 antibody    Bi-Test Reagents (FITC/RPE); Bi-Test(tm) Reagents
 Applications Tested/Suitable for anti-CD3 - CD19 antibody   

Flow Cytometry (FC/FACS)

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NCBI/Uniprot data below describe general gene information for CD3 - CD19. It may not necessarily be applicable to this product.
 NCBI GI #    4502671
 NCBI GeneID    916
 NCBI Accession #    NP_000724.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000733.3 [Other Products]
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 UniProt Primary Accession #    P07766 [Other Products]
 UniProt Secondary Accession #    A8K997 [Other Products]
 UniProt Related Accession #    P07766 [Other Products]
 Molecular Weight    23,147 Da
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 NCBI Official Full Name    T-cell surface glycoprotein CD3 epsilon chain
 NCBI Official Synonym Full Names    CD3e molecule, epsilon (CD3-TCR complex)
 NCBI Official Symbol    CD3E [Similar Products]
 NCBI Official Synonym Symbols   
T3E; TCRE
[Similar Products]
 NCBI Protein Information    T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
 UniProt Protein Name    T-cell surface glycoprotein CD3 epsilon chain
 UniProt Synonym Protein Names   
T-cell surface antigen T3/Leu-4 epsilon chain
 UniProt Gene Name    CD3E [Similar Products]
 UniProt Synonym Gene Names    T3E [Similar Products]
 UniProt Entry Name    CD3E_HUMAN
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 NCBI Summary for CD3 - CD19    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD3 - CD19    Function: The CD3 complex mediates signal transduction.

Subunit structure: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. Ref.12 Ref.13

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like (immunoglobulin-like) domain.Contains 1 ITAM domain.
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 Research Articles on CD3 - CD19    1. ABCB1 homozygous 3435 TT carrier subjects showed the lowest Pgp activity compared with 3435 CT and CC carriers of renal transplant patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD3 - CD19 antibodyPathways associated with anti-CD3 - CD19 antibody
 Reference Product  PubMed Publications
 CD4 antibody  >61 publications with CD3 - CD19 and CD4
 ZAP70 antibody  >15 publications with CD3 - CD19 and ZAP70
 LCK antibody  >14 publications with CD3 - CD19 and LCK
 CD3D antibody  >11 publications with CD3 - CD19 and CD3D
 CD3G antibody  >6 publications with CD3 - CD19 and CD3G
 CD8A antibody  >4 publications with CD3 - CD19 and CD8A
 SYK antibody  >4 publications with CD3 - CD19 and SYK
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Downstream TCR Signaling Pathway antibodies  Downstream TCR Signaling Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Generation Of Second Messenger Molecules Pathway antibodies  Generation Of Second Messenger Molecules Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
Diseases associated with anti-CD3 - CD19 antibodyOrgans/Tissues associated with anti-CD3 - CD19 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >50 publications with CD3 - CD19 and Immune System Diseases
 Neoplasms Antibodies  >45 publications with CD3 - CD19 and Neoplasms
 Lymphoma Antibodies  >26 publications with CD3 - CD19 and Lymphoma
 Inflammation Antibodies  >17 publications with CD3 - CD19 and Inflammation
 Immunologic Deficiency Syndromes Antibodies  >13 publications with CD3 - CD19 and Immunologic Deficiency Syndromes
 Necrosis Antibodies  >11 publications with CD3 - CD19 and Necrosis
 Neoplasms, Experimental Antibodies  >7 publications with CD3 - CD19 and Neoplasms, Experimental
 Lung Diseases Antibodies  >5 publications with CD3 - CD19 and Lung Diseases
 Drug Toxicity Antibodies  >5 publications with CD3 - CD19 and Drug Toxicity
 Carcinoma Antibodies  >5 publications with CD3 - CD19 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >177 publications with CD3 - CD19 and Blood
 Thymus Antibodies  >44 publications with CD3 - CD19 and Thymus
 Spleen Antibodies  >31 publications with CD3 - CD19 and Spleen
 Lymph Node Antibodies  >15 publications with CD3 - CD19 and Lymph Node
 Liver Antibodies  >10 publications with CD3 - CD19 and Liver
 Intestine Antibodies  >9 publications with CD3 - CD19 and Intestine
 Brain Antibodies  >6 publications with CD3 - CD19 and Brain
 Lung Antibodies  >6 publications with CD3 - CD19 and Lung
 Kidney Antibodies  >6 publications with CD3 - CD19 and Kidney
 Heart Antibodies  >3 publications with CD3 - CD19 and Heart
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