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anti-CD3 antibody :: Mouse CD3 Antibody

Scan QR to view Datasheet Catalog #    MBS670527 anti-CD3 antibody
Unit / Price
25 Tests  /  $130 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD3, Antibody

★Popular Item★
 Also Known As   

Mouse Anti-Human CD3-FITC

 Product Synonym Names    CD3 epsilon, T3E, TCRE, Leu-4, T3
 Product Gene Name   

anti-CD3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P79951
 Isotype    Mouse(BALB/c)IgG1 kappa
 Clone Number    UCHT1
 Host    Mouse
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 Specificity    Human CD3; Mr 20 kDa
 Form/Format    Fluorescein (FITC)
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 Immunogen    Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes
    
 Warning    Some reagents contain sodium azide.
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 Preparation and Storage    The fluorescein (FITC) conjugate is supplied as 25 tests in 0.25 mL or 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
 Other Notes    Small volumes of anti-CD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD3 antibody

   CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ? chain of the CD3/TCR complex.
 Applications Tested/Suitable for anti-CD3 antibody   

Flow Cytometry- Quality Tested 1,6-11

 Application Notes for anti-CD3 antibody    Flow Cytometry:
Purified (UNLB) antibody: <= 1ug/106 cells
FITC, BIOT, PE, APC, SPRD, CY5, PE/CY7/APC/CY7, PACBLU, AF488, AF647, and AF700 conjugates: 10ul/106
For flow cytometry, the suggested use of these reagents is in a final volume of 100ul.

Since applications vary, you should determine the optimum working dilution for the product that is appropriate for your specific need.
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NCBI/Uniprot data below describe general gene information for CD3. It may not necessarily be applicable to this product.
 NCBI GI #    1914807
 NCBI Accession #    CAA72995.1 [Other Products]
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 UniProt Primary Accession #    P79951 [Other Products]
 UniProt Secondary Accession #    O13176 [Other Products]
 Molecular Weight    18,897 Da
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 NCBI Official Full Name    cd3
 UniProt Protein Name    CD3gamma/delta
 UniProt Synonym Protein Names   
CD3gamma/delta
 Protein Family    CD302 antigen
 UniProt Gene Name    cd3g [Similar Products]
 UniProt Entry Name    P79951_XENLA
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-CD3 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with CD3 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with CD3 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CD3 and Liver Neoplasms
 Kidney Diseases Antibodies  >1 publications with CD3 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >1 publications with CD3 and Neoplasms, Experimental
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