NP_036231.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,986 Da
NCBI Official Full Name
DNA-directed RNA polymerase I subunit RPA34
NCBI Official Synonym Full Names
CD3e molecule, epsilon associated protein
NCBI Protein Information
DNA-directed RNA polymerase I subunit RPA34; A34.5; antisense to ERCC 1; CD3E-associated protein; antisense to ERCC-1 protein; CD3 epsilon associated protein; CD3-epsilon-associated protein; RNA polymerase I-associated factor PAF49; CD3e antigen, epsilon polypeptide associated protein
UniProt Protein Name
DNA-directed RNA polymerase I subunit RPA34
UniProt Synonym Protein Names
A34.5; Antisense to ERCC-1 protein; ASE-1; CD3-epsilon-associated protein; CAST; CD3E-associated protein; RNA polymerase I-associated factor PAF49
UniProt Synonym Gene Names
UniProt Entry Name
RPA34_HUMAN
UniProt Comments for CD3EAP
ASE-1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Belongs to the eukaryotic RPA34 RNA polymerase subunit family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Transcription initiation complex
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleolus; RNA polymerase I transcription factor complex; chromosome; nucleus; DNA-directed RNA polymerase I complex
Molecular Function: DNA-directed RNA polymerase activity
Biological Process: negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic; transmembrane receptor protein tyrosine kinase signaling pathway; rRNA transcription
Research Articles on CD3EAP
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Products associated with anti-CD3EAP antibody
Pathways associated with anti-CD3EAP antibody
Diseases associated with anti-CD3EAP antibody
Organs/Tissues associated with anti-CD3EAP antibody
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