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| Product Name
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CD70, Antibody
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| Also Known As
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CD70 Antibody
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| Product Synonym Names
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CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD70; CD27L; CD27LG; TNFSF7
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| OMIM
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602840
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| 3D Structure
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ModBase 3D Structure for P32970
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| Host
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Rabbit
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| Species Reactivity
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Human
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| Other Notes
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Small volumes of anti-CD70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-CD70 antibody
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Western Blot (WB)
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TOP
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| NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product. |
| NCBI GI #
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21431837
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| NCBI GeneID
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970
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| NCBI Accession #
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P32970.2
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[Other Products]
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| UniProt Primary Accession #
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P32970
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[Other Products]
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| UniProt Secondary Accession #
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Q53XX4; Q96J57; B4DPR8
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[Other Products]
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| UniProt Related Accession #
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P32970
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[Other Products]
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| Molecular Weight
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23,438 Da
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TOP
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| NCBI Official Full Name
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CD70 antigen
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| NCBI Official Synonym Full Names
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CD70 molecule
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| NCBI Official Symbol
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CD70
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[Similar Products]
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| NCBI Official Synonym Symbols
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CD27L; CD27LG; TNFSF7
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[Similar Products]
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| NCBI Protein Information
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CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7
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| UniProt Protein Name
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CD70 antigen
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| UniProt Synonym Protein Names
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CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
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| Protein Family
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CD70 antigen
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| UniProt Gene Name
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CD70
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[Similar Products]
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| UniProt Synonym Gene Names
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CD27L; CD27LG; TNFSF7; CD27-L
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[Similar Products]
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| UniProt Entry Name
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CD70_HUMAN
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| NCBI Summary for CD70
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
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| UniProt Comments for CD70
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CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family.
Protein type: Cytokine; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13
Cellular Component: extracellular space; integral to plasma membrane; plasma membrane
Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding
Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
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TOP
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| Research Articles on CD70
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1. CD70 is overexpressed in systemic lupus erythematosus CD4+ T cells, but expression is not linked to the typical clinical and serological parameters associated with the disease.
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TOP
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with anti-CD70 antibody | Pathways associated with anti-CD70 antibody |
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| Diseases associated with anti-CD70 antibody | Organs/Tissues associated with anti-CD70 antibody |
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TOP
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Antibody 
