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anti-CD70 antibody :: Rabbit anti-Human CD70 Antibody

Scan QR to view Datasheet Catalog #    MBS8508792 anti-CD70 antibody
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD70, Antibody

 Also Known As   

CD70 Antibody

 Product Synonym Names    CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD70; CD27L; CD27LG; TNFSF7
 Product Gene Name   

anti-CD70 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602840
 3D Structure    ModBase 3D Structure for P32970
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 Host    Rabbit
 Species Reactivity    Human
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 Other Notes    Small volumes of anti-CD70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CD70 antibody   

Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product.
 NCBI GI #    21431837
 NCBI GeneID    970
 NCBI Accession #    P32970.2 [Other Products]
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 UniProt Primary Accession #    P32970 [Other Products]
 UniProt Secondary Accession #    Q53XX4; Q96J57; B4DPR8 [Other Products]
 UniProt Related Accession #    P32970 [Other Products]
 Molecular Weight    23,438 Da
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 NCBI Official Full Name    CD70 antigen
 NCBI Official Synonym Full Names    CD70 molecule
 NCBI Official Symbol    CD70 [Similar Products]
 NCBI Official Synonym Symbols   
CD27L; CD27LG; TNFSF7
[Similar Products]
 NCBI Protein Information    CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7
 UniProt Protein Name    CD70 antigen
 UniProt Synonym Protein Names   
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
 Protein Family    CD70 antigen
 UniProt Gene Name    CD70 [Similar Products]
 UniProt Synonym Gene Names    CD27L; CD27LG; TNFSF7; CD27-L [Similar Products]
 UniProt Entry Name    CD70_HUMAN
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 NCBI Summary for CD70    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD70    CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family.

Protein type: Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
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 Research Articles on CD70    1. CD70 is overexpressed in systemic lupus erythematosus CD4+ T cells, but expression is not linked to the typical clinical and serological parameters associated with the disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD70 antibodyPathways associated with anti-CD70 antibody
 Reference Product  PubMed Publications
 CD27 antibody  >255 publications with CD70 and CD27
 CD40 antibody  >120 publications with CD70 and CD40
 TNFSF4 antibody  >30 publications with CD70 and TNFSF4
 TNFSF8 antibody  >14 publications with CD70 and TNFSF8
 DNMT1 antibody  >12 publications with CD70 and DNMT1
 TNFSF9 antibody  >9 publications with CD70 and TNFSF9
 FASLG antibody  >7 publications with CD70 and FASLG
 CD40LG antibody  >5 publications with CD70 and CD40LG
 SIVA1 antibody  >2 publications with CD70 and SIVA1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-CD70 antibodyOrgans/Tissues associated with anti-CD70 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >134 publications with CD70 and Necrosis
 Disease Models, Animal Antibodies  >36 publications with CD70 and Disease Models, Animal
 Inflammation Antibodies  >35 publications with CD70 and Inflammation
 Death Antibodies  >32 publications with CD70 and Death
 Neoplasms, Experimental Antibodies  >27 publications with CD70 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >21 publications with CD70 and Kidney Diseases
 Brain Diseases Antibodies  >10 publications with CD70 and Brain Diseases
 Lung Diseases Antibodies  >9 publications with CD70 and Lung Diseases
 Intestinal Diseases Antibodies  >6 publications with CD70 and Intestinal Diseases
 Eye Diseases Antibodies  >5 publications with CD70 and Eye Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >345 publications with CD70 and Blood
 Lymph Antibodies  >27 publications with CD70 and Lymph
 Skin Antibodies  >23 publications with CD70 and Skin
 Kidney Antibodies  >20 publications with CD70 and Kidney
 Lung Antibodies  >13 publications with CD70 and Lung
 Brain Antibodies  >5 publications with CD70 and Brain
 Eye Antibodies  >3 publications with CD70 and Eye
 Pancreas Antibodies  >2 publications with CD70 and Pancreas
 Prostate Antibodies  >2 publications with CD70 and Prostate
 Connective Tissue Antibodies  >2 publications with CD70 and Connective Tissue
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