NP_005182.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
T-lymphocyte activation antigen CD80
NCBI Official Synonym Full Names
CD80 molecule
NCBI Official Synonym Symbols
B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1 [Similar Products]
NCBI Protein Information
T-lymphocyte activation antigen CD80
UniProt Protein Name
T-lymphocyte activation antigen CD80
UniProt Synonym Protein Names
Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80
UniProt Synonym Gene Names
NCBI Summary for CD80/B7-1
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
UniProt Comments for CD80/B7-1
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Product References and Citations for anti-CD80/B7-1 antibody
Freeman GJ, et al. Blood 79(2):489-94, 1992. Stamper CC, et al. Nature 411(6837):617, 2001.
Research Articles on CD80/B7-1
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Products associated with anti-CD80/B7-1 antibody
Pathways associated with anti-CD80/B7-1 antibody
Diseases associated with anti-CD80/B7-1 antibody
Organs/Tissues associated with anti-CD80/B7-1 antibody
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