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anti-CD88/C5aR antibody :: anti-Human, Mouse CD88/C5aR Antibody

Scan QR to view Datasheet Catalog #    MBS859654
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD88/C5aR, Antibody

★Popular Item★
 Also Known As   

CD88/C5aR (Ab-338) Antibody

 Product Synonym Names    C5AR; C5AR1; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; CD88 antigen
 Product Gene Name   

anti-CD88/C5aR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    113995
 3D Structure    ModBase 3D Structure for P21730
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 Species Reactivity    Human, Mouse
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 Specificity    CD88/C5aR (Ab-338) antibody detects endogenous levels of total CD88/C5aR protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized non-phosphopeptide derived from human CD88/C5aR around the phosphorylation site of serine 338(T-R-SP-T-V).
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-CD88/C5aR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CD88/C5aR antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CD88/C5aR antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-CD88/C5aR antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
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 Testing Data of anti-CD88/C5aR antibody    Peptide-+
anti-CD88/C5aR antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-CD88/C5aR antibody    Immunohistochemistry analysis of paraffin-embedded human brain tissue using CD88/C5aR (Ab-338) antibody. Western blot analysis of extracts from HeLa cells, treated with PMA (125ng/ml, 30mins), using CD88/C5aR (Ab-338) antibody.
anti-CD88/C5aR antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-CD88/C5aR antibody    Peptide-+ Immunofluorescence analysis of HeLa cells, using CD88/C5aR (Ab-338) antibody.
anti-CD88/C5aR antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for CD88/C5aR. It may not necessarily be applicable to this product.
 NCBI GI #    4502509
 NCBI GeneID    728
 NCBI Accession #    NP_001727.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001736.3 [Other Products]
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 UniProt Primary Accession #    P21730 [Other Products]
 UniProt Related Accession #    P21730 [Other Products]
 Molecular Weight    39,336 Da
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 NCBI Official Full Name    C5a anaphylatoxin chemotactic receptor 1
 NCBI Official Synonym Full Names    complement C5a receptor 1
 NCBI Official Symbol    C5AR1 [Similar Products]
 NCBI Official Synonym Symbols   
C5A; C5AR; C5R1; CD88
[Similar Products]
 NCBI Protein Information    C5a anaphylatoxin chemotactic receptor 1
 UniProt Protein Name    C5a anaphylatoxin chemotactic receptor 1
 UniProt Synonym Protein Names   
C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
 UniProt Gene Name    C5AR1 [Similar Products]
 UniProt Synonym Gene Names    C5AR; C5R1; C5a-R; C5aR [Similar Products]
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 UniProt Comments for CD88/C5aR    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
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Product References and Citations for anti-CD88/C5aR antibody

   W Fureder, J. Immunol., Sep 1995; 155: 3152. T Werfel, J. Immunol., Aug 1996; 157: 1729. Anthony A. Floreani, J. Immunol., May 1998; 160: 5073. M Burg, J. Immunol., Dec 1996; 157: 5574.
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 Research Articles on CD88/C5aR    1. the role of the active fragment complement C5a receptor (C5aR) in dental nerve regeneration in regards to local secretion of nerve growth factor (NGF) upon carious injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD88/C5aR antibodyPathways associated with anti-CD88/C5aR antibody
 Reference Product  PubMed Publications
 RPS19 antibody  >1 publications with CD88/C5aR and RPS19
 GNAI2 antibody  >1 publications with CD88/C5aR and GNAI2
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
Diseases associated with anti-CD88/C5aR antibodyOrgans/Tissues associated with anti-CD88/C5aR antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >29 publications with CD88/C5aR and Inflammation
 Immune System Diseases Antibodies  >15 publications with CD88/C5aR and Immune System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with CD88/C5aR and Cardiovascular Diseases
 Lung Diseases Antibodies  >5 publications with CD88/C5aR and Lung Diseases
 Lung Injury Antibodies  >3 publications with CD88/C5aR and Lung Injury
 Heart Diseases Antibodies  >3 publications with CD88/C5aR and Heart Diseases
 Necrosis Antibodies  >3 publications with CD88/C5aR and Necrosis
 Neoplasms Antibodies  >3 publications with CD88/C5aR and Neoplasms
 Shock, Septic Antibodies  >3 publications with CD88/C5aR and Shock, Septic
 Atherosclerosis Antibodies  >2 publications with CD88/C5aR and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >38 publications with CD88/C5aR and Blood
 Bone Marrow Antibodies  >4 publications with CD88/C5aR and Bone Marrow
 Intestine Antibodies  >4 publications with CD88/C5aR and Intestine
 Placenta Antibodies  >2 publications with CD88/C5aR and Placenta
 Uterus Antibodies  >1 publications with CD88/C5aR and Uterus
 Prostate Antibodies  >1 publications with CD88/C5aR and Prostate
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