NP_008996.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,468 Da
NCBI Official Full Name
hsp90 co-chaperone Cdc37
NCBI Official Synonym Full Names
cell division cycle 37
NCBI Official Synonym Symbols
NCBI Protein Information
hsp90 co-chaperone Cdc37
UniProt Protein Name
Hsp90 co-chaperone Cdc37
UniProt Synonym Protein Names
Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37
UniProt Synonym Gene Names
NCBI Summary for CDC37
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
UniProt Comments for CDC37
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206).
Research Articles on CDC37
Precautions
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Disclaimer
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Products associated with anti-CDC37 antibody
Pathways associated with anti-CDC37 antibody
Diseases associated with anti-CDC37 antibody
Organs/Tissues associated with anti-CDC37 antibody
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