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anti-CHSY1 antibody :: anti-Human, Mouse CHSY1 Antibody

Scan QR to view Datasheet Catalog #    MBS852642
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CHSY1, Antibody

 Also Known As   

CHSY1 Antibody

 Product Synonym Names    carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase II
 Product Gene Name   

anti-CHSY1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605282
 3D Structure    ModBase 3D Structure for Q86X52
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 Species Reactivity    Human, Mouse
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 Specificity    CHSY1 antibody detects endogenous levels of total CHSY1 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human CHSY1.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-CHSY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CHSY1 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CHSY1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-CHSY1 antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000
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 Testing Data of anti-CHSY1 antibody    Peptide-+
anti-CHSY1 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-CHSY1 antibody    Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CHSY1 antibody. Western blot analysis of extracts from HepG2 cells and K562 cells, using CHSY1 antibody.
anti-CHSY1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CHSY1. It may not necessarily be applicable to this product.
 NCBI GI #    31542309
 NCBI GeneID    22856
 NCBI Accession #    NP_055733.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014918.4 [Other Products]
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 UniProt Primary Accession #    Q86X52 [Other Products]
 UniProt Secondary Accession #    Q6UX38; Q7LFU5; Q9Y2J5 [Other Products]
 UniProt Related Accession #    Q86X52 [Other Products]
 Molecular Weight    91,784 Da
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 NCBI Official Full Name    chondroitin sulfate synthase 1
 NCBI Official Synonym Full Names    chondroitin sulfate synthase 1
 NCBI Official Symbol    CHSY1 [Similar Products]
 NCBI Official Synonym Symbols   
CHSY; CSS1; TPBS; ChSy-1
[Similar Products]
 NCBI Protein Information    chondroitin sulfate synthase 1
 UniProt Protein Name    Chondroitin sulfate synthase 1
 UniProt Synonym Protein Names   
Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1
 Protein Family    Chondroitin sulfate synthase
 UniProt Gene Name    CHSY1 [Similar Products]
 UniProt Synonym Gene Names    CHSY; CSS1; KIAA0990; ChSy-1 [Similar Products]
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 NCBI Summary for CHSY1    This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. [provided by RefSeq, Dec 2011]
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 UniProt Comments for CHSY1    Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
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Product References and Citations for anti-CHSY1 antibody

   Kitagawa H., J. Biol. Chem. 276:38721-38726(2001). Nagase T., DNA Res. 6:63-70(1999). Clark H.F., Genome Res. 13:2265-2270(2003).
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 Research Articles on CHSY1    1. CHSY1 overexpression in HCC contributes to the malignant behavior of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CHSY1 antibodyDiseases associated with anti-CHSY1 antibody
 Products by Pathway  Pathway Diagram
 Chondroitin Sulfate Biosynthesis Pathway antibodies  Chondroitin Sulfate Biosynthesis Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway antibodies  Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway Diagram
 Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway antibodies  Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 MPS I - Hurler Syndrome Pathway antibodies  MPS I - Hurler Syndrome Pathway Diagram
 MPS II - Hunter Syndrome Pathway antibodies  MPS II - Hunter Syndrome Pathway Diagram
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >4 publications with CHSY1 and Congenital Abnormalities
 Neoplasms Antibodies  >2 publications with CHSY1 and Neoplasms
 Disease Models, Animal Antibodies  >1 publications with CHSY1 and Disease Models, Animal
 Muscular Diseases Antibodies  >1 publications with CHSY1 and Muscular Diseases
 Immune System Diseases Antibodies  >1 publications with CHSY1 and Immune System Diseases
 Heart Diseases Antibodies  >1 publications with CHSY1 and Heart Diseases
 Nervous System Diseases Antibodies  >1 publications with CHSY1 and Nervous System Diseases
 Heart Defects, Congenital Antibodies  >1 publications with CHSY1 and Heart Defects, Congenital
Organs/Tissues associated with anti-CHSY1 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >6 publications with CHSY1 and Bone
 Bone Marrow Antibodies  >2 publications with CHSY1 and Bone Marrow
 Blood Antibodies  >2 publications with CHSY1 and Blood
 Heart Antibodies  >1 publications with CHSY1 and Heart
 Ear Antibodies  >1 publications with CHSY1 and Ear
 Eye Antibodies  >1 publications with CHSY1 and Eye
 Stomach Antibodies  >1 publications with CHSY1 and Stomach
 Skin Antibodies  >1 publications with CHSY1 and Skin
 Connective Tissue Antibodies  >1 publications with CHSY1 and Connective Tissue
 Testis Antibodies  >1 publications with CHSY1 and Testis
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