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anti-CIB2 antibody :: Rabbit CIB2 Antibody

Scan QR to view Datasheet Catalog #    MBS002675 anti-CIB2 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CIB2, Antibody

 Also Known As   

Rabbit CIB2 Antibody

 Product Gene Name   

anti-CIB2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 15; NC_000015.9 (78396991..78423878, complement). Location: 15q24
 OMIM    605564
 3D Structure    ModBase 3D Structure for O75838
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-CIB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CIB2 antibody   

Immunohistochemistry (IHC), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for CIB2. It may not necessarily be applicable to this product.
 NCBI GI #    5453708
 NCBI GeneID    10518
 NCBI Accession #    NP_006374.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006383.3 [Other Products]
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 UniProt Primary Accession #    O75838 [Other Products]
 UniProt Related Accession #    O75838 [Other Products]
 Molecular Weight    21,644 Da
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 NCBI Official Full Name    calcium and integrin-binding family member 2 isoform 1
 NCBI Official Synonym Full Names    calcium and integrin binding family member 2
 NCBI Official Symbol    CIB2 [Similar Products]
 NCBI Official Synonym Symbols   
KIP2; USH1J; DFNB48
[Similar Products]
 NCBI Protein Information    calcium and integrin-binding family member 2; KIP 2; 2810434I23Rik; Usher syndrome 1J (autosomal recessive); DNA-dependent protein kinase catalytic subunit-interacting protein 2
 UniProt Protein Name    Calcium and integrin-binding family member 2
 UniProt Synonym Protein Names   
Kinase-interacting protein 2
 Protein Family    Calcium and integrin-binding family
 UniProt Gene Name    CIB2 [Similar Products]
 UniProt Synonym Gene Names    KIP2; KIP 2 [Similar Products]
 UniProt Entry Name    CIB2_HUMAN
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 NCBI Summary for CIB2    The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. This suggests that the encoded protein may be a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
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 UniProt Comments for CIB2    CIB2: Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: muscle tendon junction; photoreceptor inner segment; neuromuscular junction; sarcolemma

Molecular Function: integrin binding; protein binding; calcium ion binding

Biological Process: calcium ion homeostasis; photoreceptor cell maintenance

Disease: Deafness, Autosomal Recessive 48; Usher Syndrome, Type Ij
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 Research Articles on CIB2    1. Consistent with molecular modeling predictions of calcium binding, CIB2 significantly decreased the ATP-induced calcium responses in heterologous cells, whereas mutations in deafness DFNB48 altered CIB2 effects on calcium responses
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-CIB2 antibodyOrgans/Tissues associated with anti-CIB2 antibody
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with CIB2 and Congenital Abnormalities
 Nervous System Diseases Antibodies  >1 publications with CIB2 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with CIB2 and Muscle
 Testis Antibodies  >1 publications with CIB2 and Testis
 Brain Antibodies  >1 publications with CIB2 and Brain
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