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anti-CIB2 antibody :: CIB2 Antibody

Scan QR to view Datasheet Catalog #    MBS855406
Immunohistochemistry (IHC)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CIB2, Antibody

★Popular Item★
 Also Known As   

CIB2 Antibody

 Product Synonym Names    Calcium and integrin-binding family member 2; Kinase-interacting protein 2; KIP 2; CIB2; KIP2
 Product Gene Name   

anti-CIB2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605564
 3D Structure    ModBase 3D Structure for O75838
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    CIB2 antibody detects endogenous levels of total CIB2 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human CIB2.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-CIB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CIB2 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CIB2 antibody   

Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-CIB2 antibody    IHC: 1:50-1:100
ELISA: 1:5000
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 Immunohistochemistry (IHC) of anti-CIB2 antibody    Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CIB2 antibody.
anti-CIB2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CIB2. It may not necessarily be applicable to this product.
 NCBI GI #    428980593
 NCBI GeneID    10518
 NCBI Accession #    NP_001258817.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271888.1 [Other Products]
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 UniProt Primary Accession #    O75838 [Other Products]
 UniProt Secondary Accession #    Q05BT6; B4DDF0; H0YM71 [Other Products]
 UniProt Related Accession #    O75838 [Other Products]
 Molecular Weight    15,816 Da
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 NCBI Official Full Name    calcium and integrin-binding family member 2 isoform 2
 NCBI Official Synonym Full Names    calcium and integrin binding family member 2
 NCBI Official Symbol    CIB2 [Similar Products]
 NCBI Official Synonym Symbols   
KIP2; USH1J; DFNB48
[Similar Products]
 NCBI Protein Information    calcium and integrin-binding family member 2
 UniProt Protein Name    Calcium and integrin-binding family member 2
 UniProt Synonym Protein Names   
Kinase-interacting protein 2; KIP 2
 Protein Family    Calcium and integrin-binding family
 UniProt Gene Name    CIB2 [Similar Products]
 UniProt Synonym Gene Names    KIP2; KIP 2 [Similar Products]
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 NCBI Summary for CIB2    The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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 UniProt Comments for CIB2    Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970, PubMed:26426422). May be involved in the mechanotransduction process ().
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Product References and Citations for anti-CIB2 antibody

   Seki N., Biochim. Biophys. Acta 1444:143-147(1999). The MGC Project Team, Genome Res. 14:2121-2127(2004).
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 Research Articles on CIB2    1. this study identifies CIB1 and CIB2 as host helper factors for HIV-1 replication that are required for optimal receptor-mediated viral entry
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-CIB2 antibodyOrgans/Tissues associated with anti-CIB2 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with CIB2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with CIB2 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with CIB2 and Muscle
 Eye Antibodies  >1 publications with CIB2 and Eye
 Testis Antibodies  >1 publications with CIB2 and Testis
 Brain Antibodies  >1 publications with CIB2 and Brain
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