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anti-CSNK1G1 antibody :: Rabbit CK-1 gamma 1/2/3 Antibody

Scan QR to view Datasheet Catalog #    MBS853070
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CK-1 gamma 1/2/3 (CSNK1G1), Antibody

 Also Known As   

CK-1 gamma 1/2/3 (Phospho-Tyr263) Antibody

 Product Synonym Names    CK-1g1/2/3 (Phospho-Tyr263) Antibody; Casein kinase I; gamma 1 isoform; CK1-gamma1; CSNK1G1; EC 2.7.11.1; KC1G1; kinase CK1-gamma1
 Product Gene Name   

anti-CSNK1G1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606274
 3D Structure    ModBase 3D Structure for Q9HCP0
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    CK-1gamma1/2/3 (Phospho-Tyr263) antibody detects endogenous levels of CK-1gamma1/2/3 only when phosphorylated at tyrosine 263.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation s
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized phosphopeptide derived from human CK-1gamma1/2/3 around the phosphorylation site of tyrosine 263 (E-R-YP-Q-K).
 All Sites    Human: Tyr263/264/261; Mouse: Tyr263/264/261; Rat: Tyr263/264/261
 Pathway    Phospho-specific
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-CSNK1G1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CSNK1G1 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-CSNK1G1 antibody   

Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-CSNK1G1 antibody    IHC: 1:50~1:100, ELISA: 1:20000
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 Testing Data of anti-CSNK1G1 antibody    P-peptide - +
anti-CSNK1G1 antibody Testing Data image
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 Testing Data #2 of anti-CSNK1G1 antibody    Immunohistochemistry analysis of paraffin-embedded human brain tissue using CK-1gamma1/2/3 (Phospho-Tyr263) antibody.
CK-1gamma1/2/3 (Phospho-Tyr263) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.
anti-CSNK1G1 antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for CSNK1G1. It may not necessarily be applicable to this product.
 NCBI GI #    98986450
 NCBI GeneID    53944
 NCBI Accession #    NP_071331.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022048.3 [Other Products]
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 UniProt Primary Accession #    Q9HCP0 [Other Products]
 UniProt Secondary Accession #    Q5JPH1; Q96AE9; Q9HCP1 [Other Products]
 UniProt Related Accession #    Q9HCP0 [Other Products]
 Molecular Weight    45,414 Da [Similar Products]
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 NCBI Official Full Name    casein kinase I isoform gamma-1
 NCBI Official Synonym Full Names    casein kinase 1, gamma 1
 NCBI Official Symbol    CSNK1G1 [Similar Products]
 NCBI Official Synonym Symbols   
CK1gamma1
[Similar Products]
 NCBI Protein Information    casein kinase I isoform gamma-1; CKI-gamma 1
 UniProt Protein Name    Casein kinase I isoform gamma-1
 Protein Family    Casein kinase
 UniProt Gene Name    CSNK1G1 [Similar Products]
 UniProt Synonym Gene Names    CKI-gamma 1 [Similar Products]
 UniProt Entry Name    KC1G1_HUMAN
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 NCBI Summary for CSNK1G1    This gene encodes a member of the casein kinase I gene family. The encoded protein is a serine/threonine kinase that phosphorylates acidic proteins, and participates in pathways for cell growth. [provided by RefSeq, Nov 2011]
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 UniProt Comments for CSNK1G1    CK1G1: an ubiquitous protein kinase of the CK1 family. Involved in growth and morphogenesis. Two splice variant isoforms have been described.

Protein type: Kinase, protein; Protein kinase, CK1; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 15q22.1-q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; endocytosis
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Product References and Citations for anti-CSNK1G1 antibody

   Kusuda J., Cytogenet. Cell Genet. 90:298-302(2000).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Hillman R.T.,Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).
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 Research Articles on CSNK1G1    1. CK1gamma1 phosphorylates p65 and consequently promotes its degradation by ubiquitin E3 ligases CUL2 and COMMD1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CSNK1G1 antibodyOrgans/Tissues associated with anti-CSNK1G1 antibody
 Products by Pathway  Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 P53 Pathway antibodies  P53 Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CSNK1G1 and Brain
 Testis Antibodies  >1 publications with CSNK1G1 and Testis
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