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anti-CK-1 gamma 1/2/3 antibody :: CK-1 gamma 1/2/3 Antibody

Scan QR to view Datasheet Catalog #    MBS853070
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CK-1 gamma 1/2/3, Antibody

 Also Known As   

CK-1 gamma 1/2/3 (Phospho-Tyr263) Antibody

 Product Synonym Names    Casein kinase I, gamma 1 isoform; CK1-gamma1; CSNK1G1; EC; KC1G1; kinase CK1-gamma1
 Product Gene Name   

anti-CK-1 gamma 1/2/3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606274
 3D Structure    ModBase 3D Structure for Q9HCP0
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody detects endogenous levels of CK-1 gamma 1/2/3 only when phosphorylated at tyrosine 263.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized phosphopeptide derived from human CK-1 gamma 1/2/3 around the phosphorylation site of tyrosine 263 (E-R-YP-Q-K).
 All Sites    Human: Tyr263/264/261
Mouse: Tyr263/264/261
Rat: Tyr263/264/261
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-CK-1 gamma 1/2/3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CK-1 gamma 1/2/3 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CK-1 gamma 1/2/3 antibody   

Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-CK-1 gamma 1/2/3 antibody    IHC: 1:50-1:100
ELISA: 1:20000
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 Testing Data of anti-CK-1 gamma 1/2/3 antibody    P-peptide-+
anti-CK-1 gamma 1/2/3 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-CK-1 gamma 1/2/3 antibody    Immunohistochemistry analysis of paraffin-embedded human brain tissue using CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody. CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.
anti-CK-1 gamma 1/2/3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CK-1 gamma 1/2/3. It may not necessarily be applicable to this product.
 NCBI GI #    1044873352
 NCBI GeneID    53944
 NCBI Accession #    NP_001316535.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001329606.1 [Other Products]
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 UniProt Primary Accession #    Q9HCP0 [Other Products]
 UniProt Secondary Accession #    Q5JPH1; Q96AE9; Q9HCP1 [Other Products]
 UniProt Related Accession #    Q9HCP0 [Other Products]
 Molecular Weight    45,414 Da
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 NCBI Official Full Name    casein kinase I isoform gamma-1 isoform 1
 NCBI Official Synonym Full Names    casein kinase 1 gamma 1
 NCBI Official Symbol    CSNK1G1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    casein kinase I isoform gamma-1
 UniProt Protein Name    Casein kinase I isoform gamma-1
 UniProt Gene Name    CSNK1G1 [Similar Products]
 UniProt Synonym Gene Names    CKI-gamma 1 [Similar Products]
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 NCBI Summary for CK-1 gamma 1/2/3    This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]
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 UniProt Comments for CK-1 gamma 1/2/3    Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (). Phosphorylates CLSPN.
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Product References and Citations for anti-CK-1 gamma 1/2/3 antibody

   Kusuda J., Cytogenet. Cell Genet. 90:298-302(2000). The MGC Project Team; Genome Res. 14:2121-2127(2004). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).
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 Research Articles on CK-1 gamma 1/2/3    1. CK1gamma1 phosphorylates p65 and consequently promotes its degradation by ubiquitin E3 ligases CUL2 and COMMD1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CK-1 gamma 1/2/3 antibodyDiseases associated with anti-CK-1 gamma 1/2/3 antibody
 Products by Pathway  Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Wnt Signaling Pathway Netpath antibodies  Wnt Signaling Pathway Netpath Diagram
 P53 Pathway antibodies  P53 Pathway Diagram
 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >1 publications with CK-1 gamma 1/2/3 and Vascular Diseases
 Disease Models, Animal Antibodies  >1 publications with CK-1 gamma 1/2/3 and Disease Models, Animal
 Depressive Disorder Antibodies  >1 publications with CK-1 gamma 1/2/3 and Depressive Disorder
 Nervous System Diseases Antibodies  >1 publications with CK-1 gamma 1/2/3 and Nervous System Diseases
Organs/Tissues associated with anti-CK-1 gamma 1/2/3 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with CK-1 gamma 1/2/3 and Vascular
 Brain Antibodies  >1 publications with CK-1 gamma 1/2/3 and Brain
 Testis Antibodies  >1 publications with CK-1 gamma 1/2/3 and Testis
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