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anti-CLTR1 antibody :: Rabbit anti-Human CLTR1 Antibody

Scan QR to view Datasheet Catalog #    MBS000142 anti-CLTR1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CLTR1, Antibody

 Also Known As   

Rabbit CLTR1 Antibody

 Product Gene Name   

anti-CLTR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: X; NC_000023.10 (77528130..77583087, complement). Location: Xq13.2-q21.1
 OMIM    300201
 3D Structure    ModBase 3D Structure for Q9Y271
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 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-CLTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CLTR1 antibody   

ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for CLTR1. It may not necessarily be applicable to this product.
 NCBI GI #    5729798
 NCBI GeneID    10800
 NCBI Accession #    NP_006630.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006639.2 [Other Products]
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 UniProt Primary Accession #    Q9Y271 [Other Products]
 UniProt Secondary Accession #    Q5JS94; Q8IV19; B2R954; D3DTE4 [Other Products]
 UniProt Related Accession #    Q9Y271 [Other Products]
 Molecular Weight    38,541 Da
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 NCBI Official Full Name    cysteinyl leukotriene receptor 1
 NCBI Official Synonym Full Names    cysteinyl leukotriene receptor 1
 NCBI Official Symbol    CYSLTR1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    cysteinyl leukotriene receptor 1; LTD4 receptor; G-protein coupled receptor HG55; cysteinyl leukotriene D4 receptor
 UniProt Protein Name    Cysteinyl leukotriene receptor 1
 UniProt Synonym Protein Names   
Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81
 UniProt Gene Name    CYSLTR1 [Similar Products]
 UniProt Synonym Gene Names    CYSLT1; CysLTR1 [Similar Products]
 UniProt Entry Name    CLTR1_HUMAN
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 NCBI Summary for CLTR1    The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CLTR1    CYSLTR1: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: Xq13.2-q21.1

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; calcium ion transport; positive regulation of vasoconstriction; defense response; respiratory gaseous exchange; inflammatory response; chemotaxis
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 Research Articles on CLTR1    1. Genetic variant may play a role in NSAID induced acute urticaria.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CLTR1 antibodyDiseases associated with anti-CLTR1 antibody
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 Endothelins Pathway antibodies  Endothelins Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Disease Name  Pubmed Publications
 Asthma Antibodies  >39 publications with CLTR1 and Asthma
 Inflammation Antibodies  >12 publications with CLTR1 and Inflammation
 Drug Hypersensitivity Antibodies  >10 publications with CLTR1 and Drug Hypersensitivity
 Asthma, Aspirin-Induced Antibodies  >8 publications with CLTR1 and Asthma, Aspirin-Induced
 Rhinitis Antibodies  >6 publications with CLTR1 and Rhinitis
 Urticaria Antibodies  >5 publications with CLTR1 and Urticaria
 Necrosis Antibodies  >3 publications with CLTR1 and Necrosis
 Fibrosis Antibodies  >2 publications with CLTR1 and Fibrosis
 Asthma, Exercise-Induced Antibodies  >2 publications with CLTR1 and Asthma, Exercise-Induced
 Musculoskeletal Diseases Antibodies  >2 publications with CLTR1 and Musculoskeletal Diseases
Organs/Tissues associated with anti-CLTR1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with CLTR1 and Blood
 Connective Tissue Antibodies  >1 publications with CLTR1 and Connective Tissue
 Lymph Node Antibodies  >1 publications with CLTR1 and Lymph Node
 Trachea Antibodies  >1 publications with CLTR1 and Trachea
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