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anti-COL1A1 antibody :: Collagen I Antibody

Scan QR to view Datasheet Catalog #    MBS854891
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Collagen I (COL1A1), Antibody

 Also Known As   

Collagen I Antibody

 Product Synonym Names    Collagen alpha-2(I) chain; Alpha-2 type I collagen; COL1A2
 Product Gene Name   

anti-COL1A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    120160
 3D Structure    ModBase 3D Structure for P08123
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    Collagen I antibody detects endogenous levels of total Collagen I protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from N-terminal of human Collagen I.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-COL1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-COL1A1 antibody   

Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-COL1A1 antibody    IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:5000
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 Testing Data of anti-COL1A1 antibody    Peptide-+
anti-COL1A1 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-COL1A1 antibody    Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Collagen I antibody. Immunofluorescence analysis of NIH/3T3 cells, using Collagen I antibody.
anti-COL1A1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for COL1A1. It may not necessarily be applicable to this product.
 NCBI GI #    48762934
 NCBI GeneID    1278
 NCBI Accession #    NP_000080.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000089.3 [Other Products]
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 UniProt Primary Accession #    P08123 [Other Products]
 UniProt Secondary Accession #    P02464; Q13897; Q13997; Q13998; Q14038; Q14057; Q15177; Q15947; Q16480; Q16511; Q7Z5S6 [Other Products]
 UniProt Related Accession #    P08123 [Other Products]
 Molecular Weight    129,314 Da
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 NCBI Official Full Name    collagen alpha-2(I) chain
 NCBI Official Synonym Full Names    collagen type I alpha 2 chain
 NCBI Official Symbol    COL1A2 [Similar Products]
 NCBI Official Synonym Symbols   
OI4; EDSCV; EDSARTH2
[Similar Products]
 NCBI Protein Information    collagen alpha-2(I) chain
 UniProt Protein Name    Collagen alpha-2(I) chain
 UniProt Synonym Protein Names   
Alpha-2 type I collagen
 Protein Family    Collagen
 UniProt Gene Name    COL1A2 [Similar Products]
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 NCBI Summary for COL1A1    This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
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 UniProt Comments for COL1A1    Type I collagen is a member of group I collagen (fibrillar forming collagen).
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Product References and Citations for anti-COL1A1 antibody

   Masatoshi Jinnin, Nucleic Acids Res., Mar 2005; 33: 1337-1351. B. Stefanovic, Nucleic Acids Res., Jan 2000; 28: 641-647. DE Birk, J. Cell Biol., Mar 1988; 106: 999. Christina Meyer, J. Biol. Chem., Nov 2002; 277: 45400-45407.
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 Research Articles on COL1A1    1. meta-analysis suggests COL1A2 rs42524 is a significant risk factor for Intracranial Aneurysm susceptibility.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-COL1A1 antibodyPathways associated with anti-COL1A1 antibody
 Reference Product  PubMed Publications
 SPARC antibody  >28 publications with COL1A1 and SPARC
 FN1 antibody  >10 publications with COL1A1 and FN1
 LUM antibody  >5 publications with COL1A1 and LUM
 TGFBI antibody  >4 publications with COL1A1 and TGFBI
 MMP9 antibody  >4 publications with COL1A1 and MMP9
 DCN antibody  >4 publications with COL1A1 and DCN
 BGN antibody  >3 publications with COL1A1 and BGN
 VWF antibody  >2 publications with COL1A1 and VWF
 COL5A3 antibody  >1 publications with COL1A1 and COL5A3
 CD44 antibody  >1 publications with COL1A1 and CD44
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Endothelins Pathway antibodies  Endothelins Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-COL1A1 antibodyOrgans/Tissues associated with anti-COL1A1 antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >156 publications with COL1A1 and Fibrosis
 Cardiovascular Diseases Antibodies  >81 publications with COL1A1 and Cardiovascular Diseases
 Neoplasms Antibodies  >65 publications with COL1A1 and Neoplasms
 Liver Diseases Antibodies  >39 publications with COL1A1 and Liver Diseases
 Osteoporosis Antibodies  >32 publications with COL1A1 and Osteoporosis
 Heart Diseases Antibodies  >30 publications with COL1A1 and Heart Diseases
 Necrosis Antibodies  >29 publications with COL1A1 and Necrosis
 Liver Cirrhosis Antibodies  >28 publications with COL1A1 and Liver Cirrhosis
 Inflammation Antibodies  >28 publications with COL1A1 and Inflammation
 Brain Diseases Antibodies  >22 publications with COL1A1 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >242 publications with COL1A1 and Bone
 Connective Tissue Antibodies  >176 publications with COL1A1 and Connective Tissue
 Skin Antibodies  >170 publications with COL1A1 and Skin
 Muscle Antibodies  >67 publications with COL1A1 and Muscle
 Blood Antibodies  >65 publications with COL1A1 and Blood
 Liver Antibodies  >65 publications with COL1A1 and Liver
 Embryonic Tissue Antibodies  >45 publications with COL1A1 and Embryonic Tissue
 Vascular Antibodies  >41 publications with COL1A1 and Vascular
 Lung Antibodies  >37 publications with COL1A1 and Lung
 Heart Antibodies  >35 publications with COL1A1 and Heart
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