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anti-CCNA1 antibody :: Rabbit Cyclin A1 Antibody

Scan QR to view Datasheet Catalog #    MBS001316
Western blot
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyclin A1 (CCNA1), Antibody

★Popular Item★
 Also Known As   

Rabbit Cyclin A1 Antibody

 Product Gene Name   

anti-CCNA1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 13; NC_000013.10 (37005967..37017019). Location: 13q12.3-q13
 OMIM    604036
 3D Structure    ModBase 3D Structure for P78396
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Cyclin A antibody detects endogenous levels of total Cyclin A.
 Purity/Purification    Affinity-chromatography
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-CCNA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CCNA1 antibody

   Background: CCNA1 May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family; CCNA2 a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.
 Applications Tested/Suitable for anti-CCNA1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-CCNA1 antibody    WB: 1:500~1:3000
IHC: 1:50~1:200
IF: 1:100~1:500
Optimal dilutions/concentrations should be determined by the end user.
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 Western blot of anti-CCNA1 antibody    Western blot analysis on COS7 cell lysate using Cyclin A antibody,The lane on the left is treated with the antigen-specific peptide.
anti-CCNA1 antibody Western blot image
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NCBI/Uniprot data below describe general gene information for CCNA1. It may not necessarily be applicable to this product.
 NCBI GI #    161377468
 NCBI GeneID    8900
 NCBI Accession #    NP_001104515.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001111045.1 [Other Products]
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 UniProt Primary Accession #    P78396 [Other Products]
 UniProt Secondary Accession #    Q5T3V0; Q5U0G2; Q8IY91; B7Z7E3 [Other Products]
 UniProt Related Accession #    P78396 [Other Products]
 Molecular Weight    53kDa [Similar Products]
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 NCBI Official Full Name    cyclin-A1 isoform b
 NCBI Official Synonym Full Names    cyclin A1
 NCBI Official Symbol    CCNA1 [Similar Products]
 NCBI Protein Information    cyclin-A1
 UniProt Protein Name    Cyclin-A1
 Protein Family    Cyclin
 UniProt Gene Name    CCNA1 [Similar Products]
 UniProt Entry Name    CCNA1_HUMAN
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 NCBI Summary for CCNA1    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CCNA1    CCNA1: May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Cancer Testis Antigen (CTA); Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q12.3-q13

Cellular Component: nucleoplasm; microtubule cytoskeleton; cytosol

Molecular Function: protein binding; protein kinase binding

Biological Process: G1/S-specific transcription in mitotic cell cycle; mitosis; male meiosis I; cell division; regulation of G2/M transition of mitotic cell cycle; spermatogenesis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; G1/S transition of mitotic cell cycle
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 Research Articles on CCNA1    1. Nuclear FoxO3a promotes cell cycle progression by transcriptional upregulation of cyclin A1, promoting proliferation of human anaplastic thyroid carcinoma cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CCNA1 antibodyPathways associated with anti-CCNA1 antibody
 Reference Product  PubMed Publications
 CDK2 antibody  >18 publications with CCNA1 and CDK2
 CDKN1A antibody  >7 publications with CCNA1 and CDKN1A
 CDK1 antibody  >5 publications with CCNA1 and CDK1
 CDC25A antibody  >4 publications with CCNA1 and CDC25A
 CDKN1B antibody  >3 publications with CCNA1 and CDKN1B
 E2F1 antibody  >2 publications with CCNA1 and E2F1
 BRCA1 antibody  >2 publications with CCNA1 and BRCA1
 PROCA1 antibody  >1 publications with CCNA1 and PROCA1
 KLHDC9 antibody  >1 publications with CCNA1 and KLHDC9
 INCA1 antibody  >1 publications with CCNA1 and INCA1
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with anti-CCNA1 antibodyOrgans/Tissues associated with anti-CCNA1 antibody
 Disease Name  Pubmed Publications
 Carcinoma, Squamous Cell Antibodies  >21 publications with CCNA1 and Carcinoma, Squamous Cell
 Cell Transformation, Neoplastic Antibodies  >10 publications with CCNA1 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >8 publications with CCNA1 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >6 publications with CCNA1 and Lung Neoplasms
 Lung Diseases Antibodies  >5 publications with CCNA1 and Lung Diseases
 Immune System Diseases Antibodies  >4 publications with CCNA1 and Immune System Diseases
 Nervous System Diseases Antibodies  >3 publications with CCNA1 and Nervous System Diseases
 Drug Toxicity Antibodies  >3 publications with CCNA1 and Drug Toxicity
 Ovarian Neoplasms Antibodies  >3 publications with CCNA1 and Ovarian Neoplasms
 Abnormalities, Drug-Induced Antibodies  >2 publications with CCNA1 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >21 publications with CCNA1 and Testis
 Lung Antibodies  >8 publications with CCNA1 and Lung
 Bone Marrow Antibodies  >6 publications with CCNA1 and Bone Marrow
 Brain Antibodies  >6 publications with CCNA1 and Brain
 Kidney Antibodies  >4 publications with CCNA1 and Kidney
 Vascular Antibodies  >4 publications with CCNA1 and Vascular
 Eye Antibodies  >3 publications with CCNA1 and Eye
 Cervix Antibodies  >3 publications with CCNA1 and Cervix
 Nerve Antibodies  >3 publications with CCNA1 and Nerve
 Heart Antibodies  >2 publications with CCNA1 and Heart
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