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anti-CK-19 antibody :: Rabbit Cytokeratin-19 (CK-19) Antibody

Scan QR to view Datasheet Catalog #    MBS462031 anti-CK-19 antibody
Unit / Price
0.1 mg  /  $285 +1 FREE 8GB USB
 
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 Product Name   

Cytokeratin-19 (CK-19), Antibody

★Popular Item★
 Also Known As   

Rabbit anti Cytokeratin-19 (CK-19) antibody

 Product Synonym Names    Rabbit anti-CK-19; CK19; Keratin-19 (K19); KRT19; MGC15366; K1CS; Keratin type I 40kDa.
 Product Gene Name   

anti-CK-19 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Bovine
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 Specificity    This antibody only recognizes ~40 kDa of human Cytokeratin-19. It also reacts with mouse CK-19 protein. The other species are not tested.
 Purity/Purification    The Rabbit IgG is purified by Epitope Affinity Purification.
 Form/Format    This affinity purified antibody is supplied in sterile phosphatebuffered saline (pH7.2) containing antibody stabilizer
 Concentration    Size: 100 ug/200 ul (lot specific)
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 Antigen Preparation    A synthetic peptide corresponding to the C-terminus of human Cytokeratin protein.
 Positive Control    MCF-7 cell lysate
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 Preparation and Storage    The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
 Other Notes    Small volumes of anti-CK-19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CK-19 antibody

   Cytokeratin-19 is one member of the type A (acidic) subfamily of low molecular weight keratins. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I (A) cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
 Applications Tested/Suitable for anti-CK-19 antibody   

ELISA, Western Blot, Immunohistochemistry

 Application Notes for anti-CK-19 antibody    Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 0.5-2 ug/ml
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 Molecular Weight    40 kDa
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Product References and Citations for anti-CK-19 antibody

   Yuan CC, et al. Cytokeratin-19 associated with apoptosis and chemosensitivity in human cervical cancer cells. Apoptosis. 1997; 2 (1):101-5.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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