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anti-DCT antibody :: Rabbit anti-Human, mouse DCT Antibody

Scan QR to view Datasheet Catalog #    MBS000104 anti-DCT antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DCT, Antibody

 Also Known As   

Rabbit DCT Antibody

 Product Gene Name   

anti-DCT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 13; NC_000013.10 (95091835..95131936, complement). Location: 13q32
 OMIM    191275
 3D Structure    ModBase 3D Structure for P40126
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-DCT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DCT antibody   

ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for DCT. It may not necessarily be applicable to this product.
 NCBI GI #    193788640
 NCBI GeneID    1638
 NCBI Accession #    NP_001123361.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001129889.1 [Other Products]
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 UniProt Primary Accession #    P40126 [Other Products]
 UniProt Secondary Accession #    Q09GT4 [Other Products]
 UniProt Related Accession #    P40126 [Other Products]
 Molecular Weight    59,145 Da
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 NCBI Official Full Name    L-dopachrome tautomerase isoform 2
 NCBI Official Synonym Full Names    dopachrome tautomerase
 NCBI Official Symbol    DCT [Similar Products]
 NCBI Official Synonym Symbols   
TRP-2; TYRP2
[Similar Products]
 NCBI Protein Information    L-dopachrome tautomerase; DT; TRP2; dopachrome delta-isomerase; tyrosine-related protein 2; L-dopachrome Delta-isomerase; tyrosinase-related protein 2; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
 UniProt Protein Name    L-dopachrome tautomerase
 UniProt Synonym Protein Names   
L-dopachrome Delta-isomerase; Tyrosinase-related protein 2
 Protein Family    dCTP deaminase
 UniProt Gene Name    DCT [Similar Products]
 UniProt Synonym Gene Names    TYRP2; DCT; DT; TRP-2; TRP2 [Similar Products]
 UniProt Entry Name    TYRP2_HUMAN
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 UniProt Comments for DCT    DCT: Involved in regulating eumelanin and phaeomelanin levels. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Isomerase; EC 5.3.3.12; Membrane protein, integral; Amino Acid Metabolism - tyrosine; Cell development/differentiation

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: melanosome membrane; integral to membrane; melanosome; cytosol

Molecular Function: copper ion binding; oxidoreductase activity; dopachrome isomerase activity

Biological Process: neuroblast division in the ventricular zone; positive regulation of neuroblast proliferation; epidermis development; pigmentation during development; melanin biosynthetic process from tyrosine; cell development
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 Research Articles on DCT    1. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-DCT antibodyDiseases associated with anti-DCT antibody
 Products by Pathway  Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >132 publications with DCT and Neoplasms
 Hypertension Antibodies  >67 publications with DCT and Hypertension
 Kidney Diseases Antibodies  >47 publications with DCT and Kidney Diseases
 Carcinoma Antibodies  >45 publications with DCT and Carcinoma
 Heart Diseases Antibodies  >39 publications with DCT and Heart Diseases
 Drug Toxicity Antibodies  >32 publications with DCT and Drug Toxicity
 Neoplasms, Experimental Antibodies  >30 publications with DCT and Neoplasms, Experimental
 Adenocarcinoma Antibodies  >23 publications with DCT and Adenocarcinoma
 Necrosis Antibodies  >16 publications with DCT and Necrosis
 Lung Neoplasms Antibodies  >15 publications with DCT and Lung Neoplasms
Organs/Tissues associated with anti-DCT antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >259 publications with DCT and Kidney
 Eye Antibodies  >144 publications with DCT and Eye
 Skin Antibodies  >73 publications with DCT and Skin
 Heart Antibodies  >63 publications with DCT and Heart
 Brain Antibodies  >59 publications with DCT and Brain
 Bone Antibodies  >38 publications with DCT and Bone
 Lung Antibodies  >33 publications with DCT and Lung
 Embryonic Tissue Antibodies  >20 publications with DCT and Embryonic Tissue
 Intestine Antibodies  >13 publications with DCT and Intestine
 Connective Tissue Antibodies  >12 publications with DCT and Connective Tissue
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