View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rabbit DFF (CT) BP Antibody Catalog # MBS194063 Unit / Price 0.1 mg / $520 +1 FREE 8GB USB 5x0.1 mg / $2,190 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name DFF (CT) BP, Antibody Full Product Name Anti-DFF (CT) Antibody Product Synonym Names Anti-DFF (CT) BP; DFF45 (CT) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Host Rabbit Specificity Anti-DFF (CT) BP [Rabbit antibody to peptide corresponding to aa 313-331 at C-terminus of human DNAfragmentation factor DFF.]This antibody recognizes non-cleaved (45 kD) and cleaved DFF. Form/Format 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography. Antigen Peptide corresponding to aa 313- 331 at the C-terminus of human DFF. Stabilizer None Preservatives 0.02% sodium azide. Dilutions Instructions Dilute in PBS or medium which is identical to that used in the assay system. Preparation and Storage This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles. Other Notes Small volumes of anti-DFF (CT) BP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-DFF (CT) BP antibody Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human DNA fragmentation factor (DFF) which is cleaved by caspase-3 during apoptosis was identified recently. The mouse homologue of human DFF was identified as a DNase inhibitor and was designated ICAD. Upon cleavage of DFF/ICAD, a caspase activated deoxyribonuclease (CAD) is released and activated and eventually causes the degradation of DNA in nuclei. Cleavage of CAD inhibitor molecule DFF/ICAD, which causes DNase activation and DNA degradation, is a hallmark of apoptotic cell death. Product Categories/Family for anti-DFF (CT) BP antibody Apoptosis Antibodies Applications Tested/Suitable for anti-DFF (CT) BP antibody Immunoblot, Immunoprecipitation Application Notes for anti-DFF (CT) BP antibody Immunoblotting, Immunoprecipitation : use at 1:1,000-1:2,000 dilution.Positive control: Whole cell lysate from HeLa cells. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP