NP_001013764.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
141,829 Da
NCBI Official Full Name
diacylglycerol kinase kappa
NCBI Official Synonym Full Names
diacylglycerol kinase, kappa
NCBI Protein Information
diacylglycerol kinase kappa; DGK-kappa; DAG kinase kappa; diglyceride kinase kappa; 142 kDa diacylglycerol kinase
UniProt Protein Name
Diacylglycerol kinase kappa
UniProt Synonym Protein Names
142 kDa diacylglycerol kinase; Diglyceride kinase kappa
UniProt Synonym Gene Names
UniProt Entry Name
DGKK_HUMAN
NCBI Summary for DGKK
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
UniProt Comments for DGKK
DGKK: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Belongs to the eukaryotic diacylglycerol kinase family.
Protein type: Kinase, lipid; EC 2.7.1.107
Chromosomal Location of Human Ortholog: Xp11.22
Cellular Component: cytoplasm; plasma membrane
Molecular Function: metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity
Biological Process: platelet activation; protein kinase C activation; diacylglycerol metabolic process; response to oxidative stress; blood coagulation; phosphorylation
Research Articles on DGKK
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Pathways associated with anti-DGKK antibody
Diseases associated with anti-DGKK antibody
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