NP_955452.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
DNA polymerase theta
NCBI Official Synonym Full Names
polymerase (DNA directed), theta
NCBI Protein Information
DNA polymerase theta; DNA polymerase eta
UniProt Protein Name
DNA polymerase theta
UniProt Synonym Protein Names
DNA polymerase eta
UniProt Synonym Gene Names
UniProt Entry Name
DPOLQ_HUMAN
UniProt Comments for POLQ
POLQ: Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links. Belongs to the DNA polymerase type-A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage; Transferase; EC 2.7.7.7
Chromosomal Location of Human Ortholog: 3q13.33
Cellular Component: nucleoplasm
Molecular Function: DNA-directed DNA polymerase activity; damaged DNA binding; ATP binding; single-stranded DNA-dependent ATPase activity
Biological Process: DNA repair; DNA-dependent DNA replication
Research Articles on POLQ
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Diseases associated with anti-POLQ antibody
Organs/Tissues associated with anti-POLQ antibody
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