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anti-REV3L antibody :: Rabbit anti-Human, mouse DNA Polymerase zeta Antibody

Scan QR to view Datasheet Catalog #    MBS002136 anti-REV3L antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNA Polymerase zeta (REV3L), Antibody

 Also Known As   

Rabbit DNA Polymerase zeta Antibody

 Product Gene Name   

anti-REV3L antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 6; NC_000006.11 (111620234..111804414, complement). Location: 6q21
 OMIM    602776
 3D Structure    ModBase 3D Structure for O60673
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-REV3L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-REV3L antibody   

Immunohistochemistry (IHC), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for REV3L. It may not necessarily be applicable to this product.
 NCBI GI #    153792012
 NCBI GeneID    5980
 NCBI Accession #    NP_002903.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_002912.3 [Other Products]
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 UniProt Primary Accession #    O60673 [Other Products]
 UniProt Secondary Accession #    O43214; Q5TC33 [Other Products]
 UniProt Related Accession #    O60673 [Other Products]
 Molecular Weight    352,776 Da [Similar Products]
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 NCBI Official Full Name    DNA polymerase zeta catalytic subunit
 NCBI Official Synonym Full Names    REV3-like, polymerase (DNA directed), zeta, catalytic subunit
 NCBI Official Symbol    REV3L [Similar Products]
 NCBI Official Synonym Symbols   
POLZ; REV3
[Similar Products]
 NCBI Protein Information    DNA polymerase zeta catalytic subunit; hREV3; Rev-3, yeast, homolog-like (polymerase, DNA, zeta)
 UniProt Protein Name    DNA polymerase zeta catalytic subunit
 UniProt Synonym Protein Names   
Protein reversionless 3-like
 Protein Family    DNA polymerase
 UniProt Gene Name    REV3L [Similar Products]
 UniProt Synonym Gene Names    POLZ; REV3; REV3-like; hREV3 [Similar Products]
 UniProt Entry Name    DPOLZ_HUMAN
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 UniProt Comments for REV3L    REV3: the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations.

Protein type: Transferase; EC 2.7.7.7; DNA replication

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: nucleoplasm; zeta DNA polymerase complex; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; metal ion binding; 4 iron, 4 sulfur cluster binding; DNA-directed DNA polymerase activity; nucleotide binding

Biological Process: error-prone postreplication DNA repair; DNA-dependent DNA replication; DNA repair
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 Research Articles on REV3L    1. A long-term depletion of Rev3 in cultured human cells results in massive genomic instability and severe cell cycle arrest.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-REV3L antibodyPathways associated with anti-REV3L antibody
 Reference Product  PubMed Publications
 MAD2L2 antibody  >15 publications with REV3L and MAD2L2
 Products by Pathway  Pathway Diagram
 DNA Damage Bypass Pathway antibodies  DNA Damage Bypass Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 DNA Polymerase Zeta Complex Pathway antibodies  DNA Polymerase Zeta Complex Pathway Diagram
 DNA Polymerase Zeta Complex Pathway antibodies  DNA Polymerase Zeta Complex Pathway Diagram
 Fanconi Anemia Pathway antibodies  Fanconi Anemia Pathway Diagram
 Fanconi Anemia Pathway antibodies  Fanconi Anemia Pathway Diagram
 Translesion Synthesis By DNA Polymerases Bypassing Lesion On DNA Template Pathway antibodies  Translesion Synthesis By DNA Polymerases Bypassing Lesion On DNA Template Pathway Diagram
 Translesion Synthesis By Pol Zeta Pathway antibodies  Translesion Synthesis By Pol Zeta Pathway Diagram
Diseases associated with anti-REV3L antibodyOrgans/Tissues associated with anti-REV3L antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >16 publications with REV3L and Neoplasms
 Carcinoma Antibodies  >6 publications with REV3L and Carcinoma
 Intestinal Neoplasms Antibodies  >4 publications with REV3L and Intestinal Neoplasms
 Lung Neoplasms Antibodies  >3 publications with REV3L and Lung Neoplasms
 Colonic Neoplasms Antibodies  >3 publications with REV3L and Colonic Neoplasms
 Breast Neoplasms Antibodies  >3 publications with REV3L and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with REV3L and Cell Transformation, Neoplastic
 Precancerous Conditions Antibodies  >2 publications with REV3L and Precancerous Conditions
 Drug Toxicity Antibodies  >2 publications with REV3L and Drug Toxicity
 Skin Neoplasms Antibodies  >2 publications with REV3L and Skin Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with REV3L and Lung
 Brain Antibodies  >3 publications with REV3L and Brain
 Skin Antibodies  >2 publications with REV3L and Skin
 Embryonic Tissue Antibodies  >2 publications with REV3L and Embryonic Tissue
 Thymus Antibodies  >1 publications with REV3L and Thymus
 Testis Antibodies  >1 publications with REV3L and Testis
 Blood Antibodies  >1 publications with REV3L and Blood
 Stomach Antibodies  >1 publications with REV3L and Stomach
 Kidney Antibodies  >1 publications with REV3L and Kidney
 Muscle Antibodies  >1 publications with REV3L and Muscle
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