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anti-DUSP9 antibody :: Rabbit DUSP9 Antibody

Scan QR to view Datasheet Catalog #    MBS000616 anti-DUSP9 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DUSP9, Antibody

 Also Known As   

Rabbit DUSP9 Antibody

 Product Gene Name   

anti-DUSP9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: X; NC_000023.10 (152907897..152916781). Location: Xq28
 OMIM    300134
 3D Structure    ModBase 3D Structure for Q99956
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-DUSP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DUSP9 antibody   

ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for DUSP9. It may not necessarily be applicable to this product.
 NCBI GI #    4503421
 NCBI GeneID    1852
 NCBI Accession #    NP_001386.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001395.2 [Other Products]
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 UniProt Primary Accession #    Q99956 [Other Products]
 UniProt Secondary Accession #    D3DWU5 [Other Products]
 UniProt Related Accession #    Q99956 [Other Products]
 Molecular Weight    41,868 Da
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 NCBI Official Full Name    dual specificity protein phosphatase 9
 NCBI Official Synonym Full Names    dual specificity phosphatase 9
 NCBI Official Symbol    DUSP9 [Similar Products]
 NCBI Official Synonym Symbols   
MKP4; MKP-4
[Similar Products]
 NCBI Protein Information    dual specificity protein phosphatase 9; map kinase phosphatase 4; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 4
 UniProt Protein Name    Dual specificity protein phosphatase 9
 UniProt Synonym Protein Names   
Mitogen-activated protein kinase phosphatase 4
 Protein Family    Dual specificity protein phosphatase
 UniProt Gene Name    DUSP9 [Similar Products]
 UniProt Synonym Gene Names    MKP4; MAP kinase phosphatase 4; MKP-4 [Similar Products]
 UniProt Entry Name    DUS9_HUMAN
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 NCBI Summary for DUSP9    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DUSP9    DUSP9: a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (ERK, JNK, p38). Shows selectivity for members of the ERK family, is expressed at high levels in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; EC 3.1.3.16; Protein phosphatase, dual-specificity

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: JNK cascade; protein amino acid dephosphorylation; inactivation of MAPK activity
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 Research Articles on DUSP9    1. The DUSP9 locus is a common susceptibility locus for type 2 diabetes across different ethnicities, and 6 loci identified in South Asian genome-wide association studies also have significant effect on susceptibility to Japanese type 2 diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DUSP9 antibodyPathways associated with anti-DUSP9 antibody
 Reference Product  PubMed Publications
 MAPK3 antibody  >5 publications with DUSP9 and MAPK3
 MAPK1 antibody  >4 publications with DUSP9 and MAPK1
 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
Diseases associated with anti-DUSP9 antibodyOrgans/Tissues associated with anti-DUSP9 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with DUSP9 and Neoplasms
 Kidney Neoplasms Antibodies  >4 publications with DUSP9 and Kidney Neoplasms
 Kidney Diseases Antibodies  >4 publications with DUSP9 and Kidney Diseases
 Inflammation Antibodies  >3 publications with DUSP9 and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with DUSP9 and Neoplasm Metastasis
 Necrosis Antibodies  >2 publications with DUSP9 and Necrosis
 Drug Toxicity Antibodies  >1 publications with DUSP9 and Drug Toxicity
 Fatty Liver Antibodies  >1 publications with DUSP9 and Fatty Liver
 Hypertrophy Antibodies  >1 publications with DUSP9 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5 publications with DUSP9 and Kidney
 Placenta Antibodies  >4 publications with DUSP9 and Placenta
 Liver Antibodies  >3 publications with DUSP9 and Liver
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