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anti-DES antibody :: Rabbit Desmin Antibody

Scan QR to view Datasheet Catalog #    MBS004437 anti-DES antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Desmin, Antibody

 Also Known As   

Rabbit Desmin Antibody

 Product Gene Name   

anti-DES antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (220283099..220291461). Location: 2q35
 OMIM    125660
 3D Structure    ModBase 3D Structure for P17661
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-DES antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-DES antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for DES. It may not necessarily be applicable to this product.
 NCBI GI #    55749932
 NCBI GeneID    1674
 NCBI Accession #    NP_001918.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001927.3 [Other Products]
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 UniProt Primary Accession #    P17661 [Other Products]
 UniProt Secondary Accession #    Q15787; Q549R7; Q549R8; Q549R9; Q8IZR1; Q8IZR6; Q8NES2; Q8NEU6; Q8TAC4; Q8TCX2; Q8TD99 [Other Products]
 UniProt Related Accession #    P17661 [Other Products]
 Molecular Weight    53,536 Da [Similar Products]
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 NCBI Official Full Name    desmin
 NCBI Official Synonym Full Names    desmin
 NCBI Official Symbol    DES [Similar Products]
 NCBI Official Synonym Symbols   
CSM1; CSM2
[Similar Products]
 NCBI Protein Information    desmin; intermediate filament protein
 UniProt Protein Name    Desmin
 Protein Family    Desmin
 UniProt Gene Name    DES [Similar Products]
 UniProt Entry Name    DESM_HUMAN
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 NCBI Summary for DES    This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DES    desmin: a class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: intermediate filament; fascia adherens; Z disc; cytosol; neuromuscular junction; sarcolemma

Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; cytoskeletal protein binding

Biological Process: muscle contraction; cytoskeleton organization and biogenesis; regulation of heart contraction; muscle filament sliding

Disease: Cardiomyopathy, Dilated, 1i; Scapuloperoneal Syndrome, Neurogenic, Kaeser Type; Myopathy, Myofibrillar, 1; Muscular Dystrophy, Limb-girdle, Type 2r
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 Research Articles on DES    1. Phenotypic features in patients with desmin tail domain mutations are similar to those in patients with mutations localized in the 1B and 2B alpha-helical domains.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DES antibodyPathways associated with anti-DES antibody
 Reference Product  PubMed Publications
 SHBG antibody  >41 publications with DES and SHBG
 DSP antibody  >30 publications with DES and DSP
 S100B antibody  >8 publications with DES and S100B
 NEB antibody  >5 publications with DES and NEB
 PKD1 antibody  >3 publications with DES and PKD1
 CAPN1 antibody  >3 publications with DES and CAPN1
 S100A1 antibody  >1 publications with DES and S100A1
 ROCK1 antibody  >1 publications with DES and ROCK1
 AURKB antibody  >1 publications with DES and AURKB
 Products by Pathway  Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
Diseases associated with anti-DES antibodyOrgans/Tissues associated with anti-DES antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >11067 publications with DES and Neoplasms
 Nervous System Diseases Antibodies  >8276 publications with DES and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >7945 publications with DES and Cardiovascular Diseases
 Heart Diseases Antibodies  >4601 publications with DES and Heart Diseases
 Carcinoma Antibodies  >3319 publications with DES and Carcinoma
 Drug Toxicity Antibodies  >3245 publications with DES and Drug Toxicity
 Inflammation Antibodies  >2975 publications with DES and Inflammation
 Pain Antibodies  >2592 publications with DES and Pain
 Liver Diseases Antibodies  >2148 publications with DES and Liver Diseases
 Thrombosis Antibodies  >1934 publications with DES and Thrombosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16501 publications with DES and Blood
 Brain Antibodies  >8281 publications with DES and Brain
 Vascular Antibodies  >4935 publications with DES and Vascular
 Muscle Antibodies  >4766 publications with DES and Muscle
 Heart Antibodies  >4371 publications with DES and Heart
 Liver Antibodies  >4321 publications with DES and Liver
 Bone Antibodies  >3765 publications with DES and Bone
 Skin Antibodies  >2942 publications with DES and Skin
 Lung Antibodies  >2928 publications with DES and Lung
 Nerve Antibodies  >2579 publications with DES and Nerve
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