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anti-EIF3K antibody :: Rabbit anti-Human, Mouse EIF3K Antibody

Scan QR to view Datasheet Catalog #    MBS852613
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EIF3K, Antibody

 Also Known As   

EIF3K Antibody

 Product Synonym Names    Eukaryotic translation initiation factor 3 subunit K; Eukaryotic translation initiation factor 3 subunit 12; eIF-3 p25; eIF-3 p28; eIF3k; Muscle-specific gene M9 protein; PLAC-24
 Product Gene Name   

anti-EIF3K antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609596
 3D Structure    ModBase 3D Structure for Q9UBQ5
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 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    EIF3K antibody detects endogenous levels of total EIF3K protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human EIF3K.
 Pathway    Intermediates
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-EIF3K antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-EIF3K antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-EIF3K antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-EIF3K antibody    WB: 1:500~1:1000, ELISA: 1:40000
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 Testing Data of anti-EIF3K antibody    Western blot analysis of extracts from HeLa cells, using EIF3K antibody.
For Research Use Only
anti-EIF3K antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for EIF3K. It may not necessarily be applicable to this product.
 NCBI GI #    10801345
 NCBI GeneID    27335
 NCBI Accession #    NP_037366.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013234.3 [Other Products]
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 UniProt Primary Accession #    Q9UBQ5 [Other Products]
 UniProt Secondary Accession #    Q96IQ0; Q9Y6D1; A8K0I9; B7ZAM9 [Other Products]
 UniProt Related Accession #    Q9UBQ5 [Other Products]
 Molecular Weight    24,484 Da
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 NCBI Official Full Name    eukaryotic translation initiation factor 3 subunit K isoform 1
 NCBI Official Synonym Full Names    eukaryotic translation initiation factor 3, subunit K
 NCBI Official Symbol    EIF3K [Similar Products]
 NCBI Official Synonym Symbols   
M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28
[Similar Products]
 NCBI Protein Information    eukaryotic translation initiation factor 3 subunit K; EIF3K; eIF-3 p28; muscle specific; muscle-specific gene M9 protein; eukaryotic translation initiation factor 3, subunit 12
 UniProt Protein Name    Eukaryotic translation initiation factor 3 subunit K
 UniProt Synonym Protein Names   
Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 proteinPLAC-24eIF-3 p25
 UniProt Gene Name    EIF3K [Similar Products]
 UniProt Synonym Gene Names    eIF3k [Similar Products]
 UniProt Entry Name    EIF3K_HUMAN
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 NCBI Summary for EIF3K    The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for EIF3K    EIF3K: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit K family.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: eukaryotic translation initiation factor 3 complex; membrane; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; translation initiation factor activity; ribosome binding

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation
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Product References and Citations for anti-EIF3K antibody

   Mayeur G.L., Eur. J. Biochem. 270:4133-4139(2003).
Nawa G., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Ye M., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
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 Research Articles on EIF3K    1. eIF3K subunit interacts directly with the PML protein.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EIF3K antibodyPathways associated with anti-EIF3K antibody
 Reference Product  PubMed Publications
 EIF3E antibody  >10 publications with EIF3K and EIF3E
 EIF3C antibody  >2 publications with EIF3K and EIF3C
 EIF3A antibody  >2 publications with EIF3K and EIF3A
 EIF3G antibody  >1 publications with EIF3K and EIF3G
 EIF3L antibody  >1 publications with EIF3K and EIF3L
 EIF3H antibody  >1 publications with EIF3K and EIF3H
 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway antibodies  L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Ribosomal Scanning And Start Codon Recognition Pathway antibodies  Ribosomal Scanning And Start Codon Recognition Pathway Diagram
Organs/Tissues associated with anti-EIF3K antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with EIF3K and Liver
 Brain Antibodies  >3 publications with EIF3K and Brain
 Adipose Tissue Antibodies  >2 publications with EIF3K and Adipose Tissue
 Muscle Antibodies  >2 publications with EIF3K and Muscle
 Blood Antibodies  >2 publications with EIF3K and Blood
 Mammary Gland Antibodies  >2 publications with EIF3K and Mammary Gland
 Connective Tissue Antibodies  >1 publications with EIF3K and Connective Tissue
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