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anti-EPOR antibody :: Rabbit EPOR Antibody

Scan QR to view Datasheet Catalog #    MBS8503871
Western Blot (WB)
Unit / Price
0.1 mL  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EPOR, Antibody

★Popular Item★
 Also Known As   

EPOR Antibody

 Product Synonym Names    EPO-R
 Product Gene Name   

anti-EPOR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    133100
 3D Structure    ModBase 3D Structure for P19235
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity purification
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 Immunogen    A synthetic peptide of human EPOR
 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-EPOR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-EPOR antibody

   This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
 Product Categories/Family for anti-EPOR antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-EPOR antibody   

Western Blot (WB)

 Application Notes for anti-EPOR antibody    WB: 1:500-1:2000
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 Western Blot (WB) of anti-EPOR antibody    Western blot analysis of extracts of various cell lines, using EPOR antibody.
anti-EPOR antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for EPOR. It may not necessarily be applicable to this product.
 NCBI GI #    4503591
 NCBI GeneID    2057
 NCBI Accession #    NP_000112.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000121.3 [Other Products]
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 UniProt Primary Accession #    P19235 [Other Products]
 UniProt Secondary Accession #    Q15443; Q2M205; B2RCG4 [Other Products]
 UniProt Related Accession #    P19235 [Other Products]
 Molecular Weight    55kDa
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 NCBI Official Full Name    erythropoietin receptor
 NCBI Official Synonym Full Names    erythropoietin receptor
 NCBI Official Symbol    EPOR [Similar Products]
 NCBI Official Synonym Symbols   
EPO-R
[Similar Products]
 NCBI Protein Information    erythropoietin receptor
 UniProt Protein Name    Erythropoietin receptor
 Protein Family    Erythropoietin receptor
 UniProt Gene Name    EPOR [Similar Products]
 UniProt Synonym Gene Names    EPO-R [Similar Products]
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 NCBI Summary for EPOR    This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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 UniProt Comments for EPOR    Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
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 Research Articles on EPOR    1. Study reports for the first evidence that EPOR modulates breast cancer cell morphology changes upon tamoxifen treatment, which result in increased formation of cell protrusions and subsequent cell death and, proposes sustained AKT phosphorylation in EPOR-overexpressing cells as a mechanism that can lead to EPOR-induced tamoxifen resistance.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EPOR antibodyPathways associated with anti-EPOR antibody
 Reference Product  PubMed Publications
 EPO antibody  >652 publications with EPOR and EPO
 JAK2 antibody  >174 publications with EPOR and JAK2
 KITLG antibody  >96 publications with EPOR and KITLG
 KIT antibody  >46 publications with EPOR and KIT
 MAPK3 antibody  >17 publications with EPOR and MAPK3
 MAPK1 antibody  >15 publications with EPOR and MAPK1
 PTPN6 antibody  >13 publications with EPOR and PTPN6
 STAT5A antibody  >12 publications with EPOR and STAT5A
 PTPN11 antibody  >11 publications with EPOR and PTPN11
 GRB2 antibody  >9 publications with EPOR and GRB2
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 EPO Receptor Signaling Pathway antibodies  EPO Receptor Signaling Pathway Diagram
 EPO Signaling Pathway antibodies  EPO Signaling Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Kit Receptor Signaling Pathway antibodies  Kit Receptor Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
Diseases associated with anti-EPOR antibodyOrgans/Tissues associated with anti-EPOR antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >237 publications with EPOR and Neoplasms
 Anemia Antibodies  >149 publications with EPOR and Anemia
 Polycythemia Antibodies  >68 publications with EPOR and Polycythemia
 Cardiovascular Diseases Antibodies  >62 publications with EPOR and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >51 publications with EPOR and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >29 publications with EPOR and Neoplasms, Experimental
 Kidney Diseases Antibodies  >29 publications with EPOR and Kidney Diseases
 Breast Neoplasms Antibodies  >28 publications with EPOR and Breast Neoplasms
 Necrosis Antibodies  >27 publications with EPOR and Necrosis
 Inflammation Antibodies  >21 publications with EPOR and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >318 publications with EPOR and Blood
 Bone Antibodies  >121 publications with EPOR and Bone
 Brain Antibodies  >103 publications with EPOR and Brain
 Kidney Antibodies  >73 publications with EPOR and Kidney
 Liver Antibodies  >66 publications with EPOR and Liver
 Heart Antibodies  >41 publications with EPOR and Heart
 Embryonic Tissue Antibodies  >32 publications with EPOR and Embryonic Tissue
 Lung Antibodies  >22 publications with EPOR and Lung
 Eye Antibodies  >21 publications with EPOR and Eye
 Skin Antibodies  >10 publications with EPOR and Skin
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