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anti-ES8L1 antibody :: Rabbit anti-Human, mouse ES8L1 Antibody

Scan QR to view Datasheet Catalog #    MBS004564 anti-ES8L1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ES8L1, Antibody

 Also Known As   

Rabbit ES8L1 Antibody

 Product Gene Name   

anti-ES8L1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (55587221..55599291). Location: 19q13.42
 OMIM    614987
 3D Structure    ModBase 3D Structure for Q8TE68
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-ES8L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ES8L1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ES8L1. It may not necessarily be applicable to this product.
 NCBI GI #    148539855
 NCBI GeneID    54869
 NCBI Accession #    NP_060199.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_017729.3 [Other Products]
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 UniProt Primary Accession #    Q8TE68 [Other Products]
 UniProt Secondary Accession #    Q71RE2; Q8NC10; Q96BB7; Q9BSQ2; Q9GZQ2; Q9NXH0 [Other Products]
 UniProt Related Accession #    Q8TE68 [Other Products]
 Molecular Weight    80,251 Da
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 NCBI Official Full Name    epidermal growth factor receptor kinase substrate 8-like protein 1 isoform b
 NCBI Official Synonym Full Names    EPS8-like 1
 NCBI Official Symbol    EPS8L1 [Similar Products]
 NCBI Official Synonym Symbols   
DRC3; EPS8R1; PP10566
[Similar Products]
 NCBI Protein Information    epidermal growth factor receptor kinase substrate 8-like protein 1; EPS8-like protein 1; EPS8-related protein 1; epidermal growth factor receptor pathway substrate 8-related protein 1
 UniProt Protein Name    Epidermal growth factor receptor kinase substrate 8-like protein 1
 UniProt Synonym Protein Names   
Epidermal growth factor receptor pathway substrate 8-related protein 1
 UniProt Gene Name    EPS8L1 [Similar Products]
 UniProt Synonym Gene Names    DRC3; EPS8R1; EPS8-like protein 1 [Similar Products]
 UniProt Entry Name    ES8L1_HUMAN
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 NCBI Summary for ES8L1    This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ES8L1    EPS8L1: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: protein complex; cytoplasm

Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; actin binding

Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ES8L1 antibody
 Reference Product  PubMed Publications
 SOS1 antibody  >1 publications with ES8L1 and SOS1
 ABI1 antibody  >1 publications with ES8L1 and ABI1
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